Agent Name

Ethyl tert-butyl ether

CAS Number

637-92-3

Formula

C6-H14-O

Major Category

Solvents

Synonyms

1,1-Dimethylethyl ethyl ether; 2-Ethoxy-2-methylpropane; 2-Methyl-2-ethoxypropane; ETBE; Ethyl 1,1-dimethylethyl ether; Ethyl tert-butyl oxide; Methyl-2-ethoxypropane; tert-Butyl ethyl ether; [ChemIDplus]

Category

Ethers (<C12)

Description

Colorless, pale yellow liquid with an unpleasant terpene-like odor; extremely flammable; [ACGIH]

Sources/Uses

An alternative gasoline additive to decrease carbon monoxide emissions; [ACGIH]

Comments

At lethal concentrations, exposed animals experience general anesthetic effects. [ChemIDplus] A skin and eye irritant; NOAEL = 500 ppm for CNS effects in rats; In 90 day inhalation studies of rats, causes liver changes (5000 ppm) and degenerative changes of spermatocytes in seminiferous tubules (1750-5000 ppm); [ACGIH]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

25 ppm

Vapor Pressure

124 mm Hg

Lethal Concentration

LC50 (mice) = 123,000 mg/m3/15 min

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Reproductive Toxin

Yes

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: