Agent Name

o-Phenylenediamine

CAS Number

95-54-5

Formula

C6-H8-N2

Major Category

Nitrogen Compounds

Synonyms

1,2-Benzenediamine; 1,2-Diaminobenzene; 1,2-Fenylendiamin [Czech] 1,2-Benzenediamine; 1,2-Diaminobenzene; 1,2-Fenylendiamin [Czech]; 1,2-Phenylenediamine; 2-Aminoaniline; C.I. 76010; C.I. Oxidation Base 16; CI 76010; CI Oxidation Base 16; OPDA; Orthamine; PODA; SQ 15500; o-Benzenediamine; o-Diaminobenzene; o-Fenylendiamin [Czech]; [ChemIDplus] UN1673

Category

Amines, Aromatic

Description

Colorless to brownish-yellow solid that darkens on exposure to light and air; [CHEMINFO]

Sources/Uses

Used as a chemical intermediate, analytical reagent, and photographic developer; [CHEMINFO]

Comments

At lethal concentrations, exposed animals have seizures and paralysis without anesthesia. [ChemIDplus] Methemoglobinemia is observed in acute animal studies. In subchronic studies, rats have anemia and elevated liver enzymes. "Critical Effects" are irritation; liver; blood; [ACGIH]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

0.1 mg/m3

Lethal Concentration

LC50 (rat) = 1,873 mg/m3

Explanatory Notes

Melting point = 219 deg F; [CAMEO]

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Processes

Industrial Processes with risk of exposure: