Agent Name

Coumaphos

CAS Number

56-72-4

Formula

C14-H16-Cl-O5-P-S

Major Category

Pesticides

Synonyms

3-Chloro-4-methyl-7-coumarinyl diethyl phosphorothioate; 3-Chloro-4-methyl-7-hydroxycoumarin diethyl thiophosphoric acid ester; 3-Chloro-4-methylumbelliferone O-ester with O,O-diethyl phosphorothioate; 3-Chloro-7-diethoxyphosphinothioyloxy-4-methylcoumarin; 3-Chloro-7-hydroxy-4-methyl-coumarin O,O-diethyl phosphorothioate; 3-Chloro-7-hydroxy-4-methyl-coumarin O-ester with O,O-diethyl phosphorothioate; Agridip; Asunthol; Asuntol; Azunthol; Baymix; Baymix 50; CO-Ral; Coumafos; Coumafosum [INN-Latin]; Coumaphos; Coumaphos [ISO]; Coumarin, 3-chloro-7-hydroxy-4-methyl-, O-ester with O,O-diethyl phosphorothioate; Cumafos [Dutch]; Cumafos [INN-Spanish]; Cumafosum; Diethyl 3-chloro-4-methylumbelliferyl thionophosphate; Diethyl thiophosphoric acid ester of 3-chloro-4-methyl-7-hydroxycoumarin; Diethyl-O-(3-chloro-4-methyl-7-coumarinyl) phosphorothioate; Diolice; Meldane; Meldone; Muscatox; Negashunt; Negasunt; O,O-Diaethyl-O-(3-chlor-4-methyl-cumarin-7-yl)-monothiophosphat [German]; O,O-Diethyl 3-chloro-4-methyl-7-umbelliferone thiophosphate; O,O-Diethyl O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl)phosphorothioate; O,O-Diethyl O-(3-chloro-4-methyl-2-oxo-2H-benzopyran-7-yl)phosphorothioate; O,O-Diethyl O-(3-chloro-4-methyl-2-oxo-2h-benzopyran-7-yl); phosphorothioate; O,O-Diethyl O-(3-chloro-4-methyl-7-coumarinyl)phosphorothioate; O,O-Diethyl O-(3-chloro-4-methylcoumarinyl-7) thiophosphate; O,O-Diethyl O-(3-chloro-4-methylumbelliferone) thiophosphate; O,O-Diethyl O-(3-chloro-4-methylumbelliferyl)phosphorothioate; O,O-Diethyl-O-(3-chloor-4-methyl-cumarin-7-yl)monothiofosfaat [Dutch]; O,O-Dietil-O-(3-cloro-4-metil-cumarin-7-il-monotiofosfato); [Italian]; O-(3-Chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) O,O-diethyl phosphorothioate; O-(3-Chloro-4-methyl-7-coumarinyl) O,O-diethylphosphorothioate; O-3-Chloro-4-methyl-7-coumarinyl O,O-diethyl phosphorothioate; OMS 485; Phosphorothioic acid, O,O-diethyl ester, O-ester with 3-chloro-7-hydroxy-4-methylcoumarin; Phosphorothioic acid, O-(3-chloro-4-methyl-2-oxo-2H-1-benzopyran-7-yl) O,O-diethyl ester; Resitox; Suntol; Thiophosphate de O,O-diethyle et de O-(3-chloro-4-methyl-7-coumarinyle) [French]; Umbethion; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Brownish crystals with a slight odor of sulfur; [CAMEO]

Sources/Uses

"Used for the control of a wide variety of livestock insects including cattle grubs, lice, scabies, flies, and ticks; the common ectoparasites of sheep, goats, horse, swine, and poultry as well as for screwworms in all these animals." [CAMEO] Used as an insecticide and ascaricide for direct application to cattle, goats, horses, sheep, and swine;

Reference Link

EXTOXNET PIP - COUMAPHOS

Exposure Assessment
BEI

Cholinesterase activity in red cells = 70% of individual's baseline, sample time discretionary; [ACGIH]

Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.05 mg/m3, inhalable fraction and vapor

Vapor Pressure

9.7E-8 mm Hg

Lethal Concentration

LC50 (rat) = 303 mg/m3

Half Life

There was no bioaccumulation in rats. 5% of a dermal dose and 70% of an oral dose were eliminated in 7 days. [EXTOXNET]

Adverse Effects
Other Poison

Organophosphate

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: