Agent Name

n-Butyl isocyanate

CAS Number

111-36-4

Formula

C5-H9-N-O

Major Category

Toxic Gases & Vapors

Synonyms

1-Isocyanatobutane; BIC; Butane, 1-isocyanato-; Butyl isocyanate; Isocyanic acid, butyl ester; UN2485; [ChemIDplus]

Category

Monoisocyanates

Description

Colorless liquid;

Sources/Uses

Used as a chemical intermediate in the production of insecticides, fungicides, and pharmaceuticals (sulfonylureas for diabetes); [HSDB]

Comments

A lachrymator; The liquid can cause severe skin irritation and permanent eye damage. Liquid causes skin burns in animal experiments; An strong irritant by inhalation similar to methyl isocyanate; [CHEMINFO]

Exposure Assessment
TIH

Yes

Vapor Pressure

17.6 mm Hg

Lethal Concentration

LC50 (rat) = 3,000 mg/m3

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: