Agent Name

Putrescine

Alternative Name

1,4-Diaminobutane

CAS Number

110-60-1

Formula

C4-H12-N2

Major Category

Nitrogen Compounds

Synonyms

1,4-Butylenediamine; 1,4-Diaminobutane; 1,4-Tetramethylenediamine; Butylenediamine; Putrescin; Tetramethyldiamine; Tetramethylenediamine; 1,4-Butanediamine; [ChemIDplus] Butane-1,4-diamine; [ToxPlanet: EFSA: DAR - Vol. 1] UN2928

Category

Amines, Aliphatic

Description

Colorless liquid with a strong odor like piperidine; mp = 23-24 deg C; [Merck Index] White solid; mp = 26.8 deg C; [ToxPlanet: EFSA: DAR - Vol. 1] White hygroscopic solid with an odor like amines; mp = 25-28 deg C; [Alfa Aesar MSDS]

Sources/Uses

Polyamine found in all cells and certain bacteria; Used in biochemical research; [Merck Index] One of three active ingredients (0.3%) in a non-lethal food attractant for the male and female Mediterranean Fruit Flies used on orchard, citrus, and other crops; [ToxPlanet: EFSA: DAR - Vol. 1]

Comments

Corrosive to rabbit skin; Causes severe damage to rabbit eyes; [ToxPlanet: EFSA: DAR - Vol. 1] Cause muscle contraction or spasticity in intraperitoneal lethal-doses studies of mice; Causes somnolence, ptosis, and urine changes in oral lethal-dose studies of rats; [RTECS] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Harmful by ingestion and skin absorption; Toxic by inhalation; Reproductive effects observed in experimental animals; [Alfa Aesar MSDS]

Exposure Assessment
Vapor Pressure

4.12 mm Hg

Lethal Concentration

LC50 (rat) = 880-1,300 mg/m3/4hr

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Toxic solid, corrosive, organic, n.o.s."

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: