Agent Name

Vanadium

CAS Number

7440-62-2

Formula

V

Major Category

Metals

Category

Elements, Metallic

Description

Silver-white metal; [Hawley]

Sources/Uses

Vanadium compounds are found in the minerals patronite, roscoelite, carnotite and vanadinite; Used in steel alloys, x-ray machines, and catalysts; [Hawley] Used in alloys, catalysts, pigments (ceramics and glass), and in batteries; Combustion of oil and coal are the most important environmental sources; [Nordberg, p. 1349, 1363]

Comments

Less than 2% absorbed after ingestion; Primarily excreted by the kidneys; Essential mineral for some bacteria, but not known to be for humans; Reported use as a supplement by athletes and body builders; Rabbits and rats have liver injury after high-dose inhalation studies for 9-12 months; Kidney injury is observed in animals after intraperitoneal injections of vanadium; Animals dying from lethal doses have paralysis of hind limbs, respiratory depression, and convulsions; [Nordberg, p. 1347-63] See "Vanadium pentoxide."

Exposure Assessment
Explanatory Notes

mp = 1900 degrees C; [Hawley]

Half Life

12 days for rats to eliminate from the kidneys after drinking water containing VOSO4; [Nordberg, p. 911]

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

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