Agent Name

Ro 15-4513

CAS Number

91917-65-6

Formula

C15-H14-N6-O3

Major Category

Other Uses

Synonyms

Ethyl-8-azido-5,6-dihydro-5-methyl-6-oxo-4H-imidazo-1,4-benzodiazepine-3-carboxylate; RO-154513; Ro 154513; Ro15-4513; 4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 8-azido-5,6-dihydro-5-methyl-6-oxo-, ethyl ester; [ChemIDplus]

Category

Biochemical Research

Description

White or beige solid; [Sigma-Aldrich MSDS]

Sources/Uses

"Ro15-4513 is a weak partial inverse agonist of the benzodiazepine class of drugs, developed by HoffmannLa Roche in the 1980s. It is structurally related to the benzodiazepine antidote flumazenil. . . . Labelling Ro15-4513 with carbon-11 leads to the possibility of its use in PET imaging of the brain." [Wikipedia] "A partial inverse agonist of benzodiazepine receptors." [ChemIDplus]

Comments

May cause irritation; [Sigma-Aldrich MSDS]

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Other Information

No other related information on this agent was found.