Agent Name

Saponins

CAS Number

8047-15-2

Major Category

Biological Agents

Synonyms

Saponin; Saponine; [ChemIDplus]

Category

Plant Toxins

Description

Solid; [Sigma-Aldrich MSDS]

Sources/Uses

Glycoside found in plants; Poisonous to lower life forms and used by the aborigines of South America for killing fish; [Merck Index] "One research use of the saponin class of natural products involves their complexation with cholesterol to form pores in cell membrane bilayers, e.g., in red cell (erythrocyte) membranes, where complexation leads to red cell lysis (hemolysis) on intravenous injection." [Wikipedia]

Comments

Essentially non-toxic by ingestion but powerful hemolytics by intravenous injection; [Merck Index] A strong eye irritant; [Sigma-Aldrich MSDS]

Exposure Assessment
Lethal Concentration

LCLo (rat) = 250 mg/m3/4hr

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.