Agent Name

Semicarbazide

CAS Number

57-56-7

Formula

C-H5-N3-O

Major Category

Nitrogen Compounds

Synonyms

Aminomocovina [Czech]; Aminourea; Carbamic acid, hydrazide; Carbamylhydrazine; Carbazamide; Hydrazine, carbamoyl-; Hydrazinecarboxamide; Semikarbazid [Czech]; Urea, amino-; [ChemIDplus] SEM; [ToxPlanet: The EFSA Journal (2005) 219, 1-36]

Category

Hydrazides

Sources/Uses

Produced in trace amounts from heat processing of jar-seals containing azodicarbonamide; [REPROTOX] Found in foods from the thermal breakdown of azodicarbonamide in sealing gaskets used on metal lids of jars and bottles; Also a metabolite of the veterinary medication nitrofurazone (banned in the EU); [ExPub: The EFSA Journal (2005) 219, 1-36]

Comments

Developmental toxicity and teratogenicity observed in rats from single 17 mg/kg doses; Teratogenicity also observed in chickens; [REPROTOX] Causes convulsion in oral, intraperitoneal, and intravenous lethal-dose studies of mice; [RTECS] See "Semicarbazide hydrochloride."

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