Agent Name

Silane, dichlorodimethyl-, reaction products with silica

CAS Number




Major Category



Silica, hydrophobic colloidal; Silane, dichloromethyl- reaction product with silica minimum number average molecular weight (in amu), 3,340,000; [ChemIDplus] Hydrophobe Kieselsre; Amorphous Hydrophobic Silicon Dioxide; Hydrophobe HDK; CABOSIL TS610 Treated Fumed Silica; Hydrophobes amorphes hochdisperses Siliciumdioxid; Hochdisperses, amorphes, hydrophobes Siliciumdioxid; Hydrophobes Aerosil; Synthetic Hydrophobic Silicon Dioxide; Treated Colloidal Silica; Treated Colloidal Silicon Dioxide; Treated Light Anhydrous Silicic Acid; Treated Silica Collidalis Anhydrica; Treated Synthetic Silica; [IUCLID]


Metalloid Compounds (Silicon)


White amorphous substance; [EPA ChAMP: Hazard Characterization] White odorless powder; [Evonik MSDS]


Used to make adhesives, paints, coatings, printing inks, resins, and synthetic rubbers, and in coating, engraving, heat treating, and allied activities; [EPA ChAMP: Hazard Characterization] Used in silicone rubber, sealants, adhesives, paints an lacquers, coating agents, colored printing inks, toners, cosmetics, and pesticides; [Evonik MSDS] Permitted for use as an inert ingredient in non-food pesticide products; [EPA]


Not a skin or eye irritant in rabbits; No significant adverse effects observed in 6-month oral study of rats at 500 mg/kg/day (only tested dose); Histopathological changes of the lungs observed in repeated-dose inhalation studies of rats at concentrations as low as 31 mg/m3; No effects to male or female reproductive organs observed in any of the studies; No evidence of carcinogenicity in rats; [EPA ChAMP: Hazard Characterization]

Exposure Assessment
Lethal Concentration

LC50 (rat) = 450 mg/m3/4hr

Links to Other NLM Databases
Toxicity Information


Chemical Information

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Related Information in HazMap

Industrial Processes with risk of exposure: