Agent Name

Thiamine hydrochloride

CAS Number

67-03-8

Formula

C12-H17-N4-O-S.Cl-H.Cl

Major Category

Biological Agents

Synonyms

Thiamine, chloride, hydrochloride; Thiamine, monohydrochloride (8CI); Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride (1:1), hydrochloride (1:1); Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride, monohydrochloride; Chloride-hydrochloride salt of thiamine; 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride monohydrochloride; Aneurine hydrochloride; Apate drops; Beatine; Bedome; Begiolan; Benerva; Bequin; Berin; Betabion; Betabion hydrochloride; Betalin S; Betaxin; Bethiazine; Beuion; Bevitex; Bevitine; Bewon; Biamine; Bithiamin; Biuno; Bivatin; Bivita; Clotiamina; Eskapen; Eskaphen; Hybee; Lixa-Beta; Metabolin; Slowten; THD; Thiadoxine; Thiamin chloride; Thiamin dichloride; Thiamin hydrochloride; Thiaminal; Thiamine chloride hydrochloride; Thiamine dichloride; Thiamine HCl; Thiamine monohydrochloride; Thiaminium chloride; Thiaminium chloride hydrochloride; Thiaminum hydrochloricum; Thiamol; Thiavit; Tiamidon; Tiaminal; Trophite; Vetalin S; Vinothiam;; Vitamin B(sub 1) hydrochloride; Vitamin B1 hydrochloride; Vitaneuron; [ChemIDplus]

Category

Vitamins and Derivatives

Description

Solid with a mild thiazole odor; [Merck Index] White to light yellow crystalline powder; Hygroscopic; [Alfa Aesar MSDS]

Sources/Uses

Used as a human and veterinary vitamin (enzyme cofactor); [Merck Index] "An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake." [ChemIDplus] Used as a flavoring agent and nutritional supplement for foods; [FDA] Permitted for use as an inert ingredient in non-food pesticide products; [EPA]

Comments

Forms a hydrate on absorbing water from atmospheric humidity; [Merck Index] Safe when used as a flavoring agent in food; [JECFA] A skin and strong eye irritant; [Alfa Aesar MSDS] See "Thiamine."

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