Agent Name

4-Aminopyridine

Alternative Name

Fampridine

CAS Number

504-24-5

Formula

C5-H6-N2

Major Category

Pesticides

Synonyms

Fampridine; 4-Pyridinamine; 4-Pyridylamine; p-Aminopyridine; gamma-Aminopyridine; Avitrol 200; Fampridine; 4-AP; Amino-4 pyridine; Avitrol [ChemIDplus]

Category

Avicides

Description

White crystals; [CAMEO] Formulated as grain bait or powder concentrate; [EXTOXNET]

Sources/Uses

Used as a chemical intermediate, a bird repellant, and a medication; [HSDB] A potassium channel blocker that is used primarily in research, but also in medicine to treat Lambert-Eaton syndrome and multiple sclerosis; [ChemiIDplus] Used as an avicide, an intermediate, and textile dye fixative; [CAMEO]

Comments

"Material may be fatal if inhaled, swallowed or absorbed through skin. Contact may cause burns to skin and eyes. Material affects neural transmission. In sufficient concentrations, material may cause metabolic acidosis, respiratory arrest, and cardiac arrhythmias." [CAMEO] Effective bird repellant as flock is frightened by distress of poisoned birds; Avitrol is a central nervous system stimulant, and as little as 60 mg causes severe poisoning in adult humans. It is readily absorbed through the skin. Symptoms of poisoning include thirst, dizziness, weakness, sweating, toxic psychosis, tremors, and seizures. Avitrol can also cause methemoglobinemia. It is an eye irritant. [EXTOXNET]

Reference Link

EXTOXNET PIP - 4-AMINOPYRIDINE

Exposure Assessment
Vapor Pressure

0.00034 mm Hg

Reference Link

EPA Pesticide Chemical Search

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Methemoglobinemia

Methemoglobinemia, Secondary

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: