Agent Name

Spermine hydrochloride

CAS Number

306-67-2

Formula

C10-H26-N4.4Cl-H

Major Category

Other Uses

Synonyms

1,4-Bis(aminopropyl)butanediamine tetrahydrochloride; 1,4-Butanediamino, N,N'-bis(3-aminopropyl), tetrahydrochloride; Gerontine tetrahydrochloride; Musculamine tetrahydrochloride; N,N'-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride; Neuridine tetrahydrochloride; Spermine HCl; Spermine tetrahydrochloride; 1,4-Butanediamine, N,N'-bis(3-aminopropyl)-, tetrahydrochloride; 1,4-Butanediamine, N1,N4-bis(3-aminopropyl)-, hydrochloride (1:4); 4,9-Diazoniadodecamethylenediammonium tetrachloride; [ChemIDplus]

Category

Biochemical Research

Description

Solid; [Merck Index] White hygroscopic powder; [Sigma-Aldrich MSDS]

Sources/Uses

Found widely in nature and essential for tissue growth; Used as a tool in biochemical research; [Merck Index] "Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine, it is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. . . . Spermine is associated with nucleic acids and is thought to stabilize helical structure, in particular, in viruses." [Wikipedia]

Comments

Causes convulsions in intraperitoneal lethal-dose studies of mice; LD50 = 370 mg/kg; [RTECS] A skin and strong eye irritant; [Sigma-Aldrich MSDS]

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Other Information

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