| Agent Name | Terpenes and Terpenoids, sweet orange-oil |
|---|---|
| CAS Number | 68647-72-3 |
| Formula | Unspecified |
| Major Category | Biological Agents |
| Synonyms | Terpenes, orange oil; Orange oil terpenes; Orange oil, terpenes; Sweet orange oil terpenes; [ChemIDplus] Citrus Clearing Solvent; Orange Terpenes; [Thermo Scientific MSDS] UN2319 |
| Category | Terpenes |
| Description | Liquid; [Reference #1] Clear colorless liquid with a sweet odor; [Thermo Scientific MSDS] |
| Sources/Uses | Monoterpene hydrocarbons are found in all plants and common in foods; Used as intermediates, odor agents, flavoring agents, and solvents for cleaning and degreasing in products including soaps, detergents, automotive care products, rubber and plastic products, polishes, and sanitation products; [Reference #1] Permitted for use as an inert ingredient in non-food pesticide products; [EPA] |
| Comments | Composed of approximately 91-95% d-limonene, 2.0-2.1% myrcene, and 1-2% alpha-pinene; Members of the monoterpene hydrocarbons category demonstrate low acute oral (rats and mice) and dermal (rabbits) toxicity; Eye irritation in rabbits, skin irritation in rabbits and humans, and skin sensitization in guinea pigs and humans; Hematological effects and splenic atrophy in repeated-dose oral studies of rats at 1,000 mg/kg/day with one category member and effects on clinical chemistry and stomach lesions at 1,500 mg/kg/day with another; Histopathological liver changes in repeated-dose oral studies of mice at 1,000 mg/kg/day; No adverse effects to reproductive organs; Effects on female fertility in rats at 1,000 mg/kg/day; Reproductive/developmental toxicity and teratogenicity in rats at dose not maternally toxic; Developmental toxicity in rats and mice at doses maternally toxic; No developmental toxicity in rabbits; [Reference #1] A skin and eye irritant; May cause skin sensitization; [Thermo Scientific MSDS] See "d-Limonene." |
| Reference Link | |
| Exposure Assessment | |
| Vapor Pressure | 0.9 mm Hg |
| Explanatory Notes | The Guide in the Emergency Response Guidebook is for "Terpene hydrocarbons, n.o.s." |
| Adverse Effects | |
| Skin Sensitizer | Yes |
| Neurotoxin | CNS Solvent Syndrome |
| Hepatotoxin | Hepatotoxin, Secondary |
| Links to Other NLM Databases | |
| Toxicity Information | |
| Chemical Information | |
| Related Information in HazMap | |
| Diseases | Occupational diseases associated with exposure to this agent: |
| Processes | Industrial Processes with risk of exposure: |
Agent Name
Terpenes and Terpenoids, sweet orange-oil
CAS Number
68647-72-3
Formula
Unspecified
Major Category
Biological Agents
Synonyms
Terpenes, orange oil; Orange oil terpenes; Orange oil, terpenes; Sweet orange oil terpenes; [ChemIDplus] Citrus Clearing Solvent; Orange Terpenes; [Thermo Scientific MSDS] UN2319
Category
Terpenes
Description
Liquid; [Reference #1] Clear colorless liquid with a sweet odor; [Thermo Scientific MSDS]
Sources/Uses
Monoterpene hydrocarbons are found in all plants and common in foods; Used as intermediates, odor agents, flavoring agents, and solvents for cleaning and degreasing in products including soaps, detergents, automotive care products, rubber and plastic products, polishes, and sanitation products; [Reference #1] Permitted for use as an inert ingredient in non-food pesticide products; [EPA]
Comments
Composed of approximately 91-95% d-limonene, 2.0-2.1% myrcene, and 1-2% alpha-pinene; Members of the monoterpene hydrocarbons category demonstrate low acute oral (rats and mice) and dermal (rabbits) toxicity; Eye irritation in rabbits, skin irritation in rabbits and humans, and skin sensitization in guinea pigs and humans; Hematological effects and splenic atrophy in repeated-dose oral studies of rats at 1,000 mg/kg/day with one category member and effects on clinical chemistry and stomach lesions at 1,500 mg/kg/day with another; Histopathological liver changes in repeated-dose oral studies of mice at 1,000 mg/kg/day; No adverse effects to reproductive organs; Effects on female fertility in rats at 1,000 mg/kg/day; Reproductive/developmental toxicity and teratogenicity in rats at dose not maternally toxic; Developmental toxicity in rats and mice at doses maternally toxic; No developmental toxicity in rabbits; [Reference #1] A skin and eye irritant; May cause skin sensitization; [Thermo Scientific MSDS] See "d-Limonene."
Reference Link
Exposure Assessment
Vapor Pressure
0.9 mm Hg
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Terpene hydrocarbons, n.o.s."
Adverse Effects
Skin Sensitizer
Yes
Neurotoxin
CNS Solvent Syndrome
Hepatotoxin
Hepatotoxin, Secondary
Links to Other NLM Databases
Toxicity Information
Chemical Information
Related Information in HazMap
Diseases
Occupational diseases associated with exposure to this agent: