Agent Name

Terpenes and Terpenoids, sweet orange-oil

CAS Number

68647-72-3

Formula

Unspecified

Major Category

Biological Agents

Synonyms

Terpenes, orange oil; Orange oil terpenes; Orange oil, terpenes; Sweet orange oil terpenes; [ChemIDplus] Citrus Clearing Solvent; Orange Terpenes; [Thermo Scientific MSDS] UN2319

Category

Terpenes

Description

Liquid; [Reference #1] Clear colorless liquid with a sweet odor; [Thermo Scientific MSDS]

Sources/Uses

Monoterpene hydrocarbons are found in all plants and common in foods; Used as intermediates, odor agents, flavoring agents, and solvents for cleaning and degreasing in products including soaps, detergents, automotive care products, rubber and plastic products, polishes, and sanitation products; [Reference #1] Permitted for use as an inert ingredient in non-food pesticide products; [EPA]

Comments

Composed of approximately 91-95% d-limonene, 2.0-2.1% myrcene, and 1-2% alpha-pinene; Members of the monoterpene hydrocarbons category demonstrate low acute oral (rats and mice) and dermal (rabbits) toxicity; Eye irritation in rabbits, skin irritation in rabbits and humans, and skin sensitization in guinea pigs and humans; Hematological effects and splenic atrophy in repeated-dose oral studies of rats at 1,000 mg/kg/day with one category member and effects on clinical chemistry and stomach lesions at 1,500 mg/kg/day with another; Histopathological liver changes in repeated-dose oral studies of mice at 1,000 mg/kg/day; No adverse effects to reproductive organs; Effects on female fertility in rats at 1,000 mg/kg/day; Reproductive/developmental toxicity and teratogenicity in rats at dose not maternally toxic; Developmental toxicity in rats and mice at doses maternally toxic; No developmental toxicity in rabbits; [Reference #1] A skin and eye irritant; May cause skin sensitization; [Thermo Scientific MSDS] See "d-Limonene."

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
Vapor Pressure

0.9 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Terpene hydrocarbons, n.o.s."

Adverse Effects
Skin Sensitizer

Yes

Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: