Agent Name

Soot (as found in occupational exposure of chimney sweeps)

Major Category

Other Uses

Synonyms

Soot

Category

Exposures, PAH-Related

Description

Black particles formed from combustion of coal, wood, fuel oil, waste oil, paper, plastics, and other organic materials and refuse; Soots contain about 60% or greater carbon content, plus inorganic and soluble organic fractions. [NTP]

Sources/Uses

Unwanted combustion by-products from fireplaces, furnaces, engine exhaust, etc. Potentially exposed workers include chimney sweeps, heating-unit service laborers, brick masons, demolition laborers, insulators, firefighters, metallurgical workers, and others who burn organic materials. [NTP]

Comments

Exposure to soots in chimney sweeps was first linked to skin (scrotal) cancer in 1775. The soluble organic fraction of soots consists of polycyclic aromatic hydrocarbons (PAHs) and there derivatives. Inorganic chemicals present in soots include a number of carcinogens: arsenic, cadmium, chromium, and nickel. [NTP] Soots are occupational carcinogens with strong associations for skin and lung cancer and a suggestive association for esophageal cancer. [Siemiatycki, p. 327] Chimney sweeps had increased risk of skin and lung cancer. [IARC]

Reference Link

IARC 2012: Soot, as found in occupational exposure of chimney-sweeps

Exposure Assessment
Reference Link

NTP: Soots

Adverse Effects
IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Human Carcinogen

Links to Other NLM Databases
Toxicity Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure:

Activities

Activities with risk of exposure: