Agent Name

Tetramethyltin

CAS Number

594-27-4

Formula

C4-H12-Sn

Major Category

Metals

Synonyms

Stannane, tetramethyl-; Tetramethyl tin; Tetramethylcin [Czech]; Tetramethylstannane; Tin, tetramethyl-; [ChemIDplus] UN3384

Category

Tin Compounds, Organic

Description

Clear colorless liquid; [Gelest MSDS]

Comments

Causes lachrymation and convulsions in inhalation lethal-concentration studies of mice; [RTECS] May cause severe eye irritation; Symptoms reported from inhalation exposure include bradycardia, hypertension, nausea, vomiting, respiratory tract irritation, abrupt variation in sinus rhythm, and short term memory loss; Higher level inhalation exposure has been reported to cause brain cell and limbic system damage; May be absorbed through skin; Oral LD50 (rat) = 195-331 mg/kg; Chronic exposure may cause memory loss, exhibition of rage and anger, and decreased sexual function; [Gelest MSDS] See "Tetraethyl tin."

Exposure Assessment
Skin Designation (ACGIH)

Yes

TIH

Yes

TLV (ACGIH)

0.1 mg/m3, as Sn

STEL (ACGIH)

0.2 mg/m3, as Sn

PEL (OSHA)

0.1 mg/m3, as Sn

MAK

0.005 mg/m3(can also occur as vapor and aerosol), 0.1 mg/m3, inhalable fraction, as Sn

IDLH (NIOSH)

25 mg/m3, as Sn

Vapor Pressure

110 mm Hg

Lethal Concentration

LCLo (mouse) = 2,550 mg/m3/10min

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Toxic by inhalation liquid, flammable, n.o.s. (Inhalation Hazard Zone B)."

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: