Agent Name

trans-1,2-Dichloroethylene

Alternative Name

trans-Acetylene dichloride

CAS Number

156-60-5

Formula

C2-H2-Cl2

Major Category

Solvents

Synonyms

(E)-1,2-Dichloroethene; (E)-1,2-Dichloroethylene; Ethylene, 1,2-dichloro-, trans-; HCC 1130t; R 1130t; trans-1,2-Dichloroethene; trans-Acetylene dichloride; trans-Dichloroethylene; Ethene, 1,2-dichloro-, (1E)-; Ethylene, 1,2-dichloro-, (E)-; 1,2-Dichloroethene, trans-; 1,2-trans-Dichloroethylene; Ethene, 1,2-dichloro-, (E)-; [ChemIDplus] trans-Acetylene dichloride; [Sigma-Aldrich MSDS] UN1150

Category

Chlorinated Aliphatics

Description

Colorless liquid with a pleasant odor; [CAMEO] Clear light yellow liquid; [Sigma-Aldrich MSDS]

Sources/Uses

Used as a solvent for fats, phenol, camphor, etc. and as an intermediated for chlorinated solvents and compounds; [Merck Index] Also used to make rubber, as a refrigerant, an additive (dyes, lacquer solutions, medicines, perfumes, and thermoplastics), and to retard fermentation; [NTP] The trans- isomer is used industrially more than the cis- isomer or the commercial mixture; [HSDB]

Comments

Forms unstable peroxides in air that may spontaneously explode; [CAMEO] A skin, eye, mucous membrane, and upper respiratory tract irritant; May cause CNS intoxication and transient renal effects; [NTP] Exposure to concentrations of 2,200 ppm causes burning of eyes, vertigo, and nausea; Twice as toxic as the cis- isomer; [HSDB] Human inhalation of 4,800 mg/m3 for 10 minutes causes sleep and hallucinations; [RTECS] A skin and strong eye irritant; Prolonged or repeated exposure may cause narcosis; Harmful by ingestion; Targets the CNS, liver, and kidney; [Sigma-Aldrich MSDS] See "1,2-Dichloroethylene, all isomers."

Reference Link

ATSDR - ToxFAQs: 1,2-Dichloroethene

Exposure Assessment
TLV (ACGIH)

200 ppm

PEL (OSHA)

200 ppm

MAK

200 ppm

Vapor Pressure

331 mm Hg

Odor Threshold Low

0.08 ppm

Odor Threshold High

1975 ppm

Lethal Concentration

LC50 (rat) = 24,100 ppm

Explanatory Notes

Vapor pressure = 200 mm Hg at 14 deg C; [NTP] Odor threshold from HSDB;

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
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Toxicity Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: