Agent Name

Triethylene glycol dimethyl ether

Alternative Name

Triglyme

CAS Number

112-49-2

Formula

C8-H18-O4

Major Category

Solvents

Synonyms

1,2-Bis(2-methoxyethoxy)ethane; 2,5,8,11-Tetraoxadodecane; Ansul Ether 161; Ethane, 1,2-bis(2-methoxyethoxy)-; Glycol, triethylene-, dimethyl ether; Glyme 4; TEGDIME; TEGDME; Triglyme; [ChemIDplus] 1,2-Bis(methoxyethoxy)ethane; Hisolve MTM; Methyltriglyme; [CAMEO]

Category

Glycol Ethers (Glymes)

Description

Liquid; [Merck Index] Colorless liquid; [ICSC] Hygroscopic; [Alfa Aesar MSDS]

Sources/Uses

Used as a solvent; [Merck Index] Used as a solvent for gases and coupling immiscible liquid; [NTP] Not produced commercially in the EU; [Glycol Ethers Online]

Comments

May have adverse effects on human reproduction, based on animal studies; [ICSC] Labeled as "May impair fertility" and "May cause harm to the unborn child" by EU regulations; [Glycol Ethers Online] Prolonged contact with air can form explosive peroxides; [CAMEO] A skin and eye irritant; [NTP] May form explosive peroxides; An irritant; May cause impaired fertility and fetal toxicity; [Alfa Aesar MSDS] See "Monoglyme."

Exposure Assessment
Vapor Pressure

0.04 mm Hg

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Reproductive Toxin

Yes

Links to Other NLM Databases
Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: