Agent Name

Trimethylsilyldiazomethane

CAS Number

18107-18-1

Formula

C4-H10-N2-Si

Major Category

Metals

Synonyms

Diazo((trimethylsilyl))methane; Diazomethyltrimethyl silane; TMSCHN2; TMSD; Silane, (diazomethyl)trimethyl-; [ChemIDplus] (Trimethylsilyl)diazomethane; [Sigma-Aldrich MSDS]

Category

Metalloid Compounds (Silicon)

Description

Greenish-yellow liquid; [HSDB]

Sources/Uses

Used as an alternative derivatizing agent for analysis of contaminants in drinking water, in the derivatization of phenols, and in organic synthesis; [HSDB]

Comments

"To this day, it is unknown whether TMSD itself was the proximal cause of death in two workers, or whether conditions of use led to the evolution of diazomethane." [Reference #1] See "Diazomethane."

Reference Link

Delayed Respiratory Fatality From Trimethylsilyldiazomethane: What Do Workers Need to Know About Potentially Hazardous Exposures?

Adverse Effects
Toxic Pneumonitis

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.