Agent Name

Phosphorus-32

CAS Number

14596-37-3

Formula

P

Major Category

Physical/Radiation

Category

Radionuclides

Sources/Uses

Used in medicine to treat ovarian cancer, leukemia, multiple myeloma, and polycythemia rubra vera; also used as a tracer in biomedical research; [Waltar, p. 280]

Comments

"There is sufficient evidence in humans that therapeutic ingestion or injection of phosphorus-32 administered as inorganic phosphate causes acute leukemia." [IARC] Half-Life: 14 days Effective Half-Life: 14 days Specific Activity: 285,000 Ci/gm Decay Mode: Beta Lung Clearance Half-Time: Weeks for phosphates of Zn2+, S3+, Mg2+, Fe3+, Bi3+, and lanthanides; Days for all other compounds; Critical Organ: Bone Internal Toxicity: High Annual Limit on Intake: 0.4 mCi Radiation Energy (MeV): Beta 1.71 (100%) Radiation Accidents: 3 accidents with 6 people exposed and no deaths; [See Glossary for references.] See "Radiation, ionizing."

Reference Link

ORCBS Isotope Information Sheets: Phosphorus-32

Adverse Effects
IARC Carcinogen

Known Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Other Information

No other related information on this agent was found.