Agent Name

Mitoxantrone hydrochloride

Alternative Name

Novantrone

CAS Number

70476-82-3

Formula

C22-H28-N4-O6.2Cl-H

Major Category

Other Uses

Synonyms

1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthraquinone dihydrochloride; 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)-, dihydrochloride; Immunex; Mitoxantrone dihydrochloride; Novantron;Novantrone; [ChemIDplus]

Category

Pharmaceuticals

Description

Crystals; [Merck Index]

Sources/Uses

Used as an antineoplastic drug; [Merck Index]

Comments

Occupational asthma in a nurse confirmed by specific bronchoprovocation testing; [Malo]

Exposure Assessment
Vapor Pressure

1.3E-20 mm Hg

Adverse Effects
Asthma

Yes

IARC Carcinogen

Possible Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: