Agent Name

Nitrogen chloride

Alternative Name

Nitrogen trichloride

CAS Number

10025-85-1

Formula

Cl3-N

Major Category

Nitrogen Compounds

Synonyms

Agene; Chlorine nitride; Trichloramine; Trichlorine nitride; Nitrogen trichloride; [ChemIDplus]

Category

Other Nitrogen Compounds

Sources/Uses

A byproduct of water chlorination, it is volatile and strongly irritating; May make the lung more susceptible to allergens; It is formed when organic matter in sweat and urine react with chlorine in swimming pools; [Reference #2]

Comments

Occupational asthma in indoor pool workers (lifeguards and a swimming teacher) confirmed by specific bronchoprovocation testing; [Malo] Chloramines include chloramide (NH2Cl), dichloramide (NHCl2), and trichloramide (NCl3). Tricloramide, also called nitrogen chloride or nitrogen trichloride, was the predominant vapor found in the indoor pool environment with a high chlorine to nitrogen ratio. All three swimming pools the study had been treated with sodium hypochlorite. Measured levels of NCl3 ranged from 0.23-0.57 mg/m3 in one pool and 0.1-0.31 in another pool. The concentration used for the challenge tests was 0.5 mg/m3. All 3 workers had immediate asthmatic reactions to the challenge tests, and one had an additional late reaction. [See Reference #1]

Reference Link

Occupational asthma caused by chloramines in indoor swimming-pool air

Exposure Assessment
Lethal Concentration

LC50 (rat) = 112 ppm/1H

Reference Link

The chlorine hypothesis: fact or fiction?

Adverse Effects
Asthma

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: