Agent Name

1-Dodecanethiol

Alternative Name

Dodecyl mercaptan

CAS Number

112-55-0

Formula

C12-H26-S

Major Category

Other Classes

Synonyms

1-Dodecyl mercaptan; n-Dodecyl mercaptan; Lauryl mercaptan; n-Lauryl mercaptan; 1-Mercaptododecane; [NIOSH]

Category

Thiols

Description

Colorless, water-white, or pale-yellow, oily liquid with a mild, skunk-like odor; Note: A solid below 15 degrees F; [NIOSH]

Sources/Uses

Used in the production of drugs, insecticides, detergents, and synthetic rubber and as a flotation agent for metal refining; [ACGIH]

Comments

This chemical is listed in the Chemotechnique Diagnostics "Shoe Series" for patch testing. [Marks, p. 376] Not highly toxic after acute exposure; Rats and mice had no adverse effects after exposure to 8-9 ppm for 1 to 6 hours. Some mice died after exposure to 8 ppm (6 hours/day, 5 days/week for 4 weeks); No adverse effects in rats exposed to 329 ppm (twenty 6-hour exposures); A dermal sensitizer; [ACGIH] Danger of skin sensitization; [MAK] See "THIOLS."

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

0.1 ppm

Vapor Pressure

2.5 mm Hg

Odor Threshold Low

0.00025 ppm

Explanatory Notes

NIOSH REL = 15 min. ceiling of 0.5 ppm; Flash point = 128 deg C; Odor threshold from ACGIH;

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Skin Sensitizer

Yes

Other Poison

Chemical Asphyxiant

Links to Other NLM Databases
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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: