Agent Name

Octamethyltrisiloxane

CAS Number

107-51-7

Formula

C8-H24-O2-Si3

Major Category

Metals

Synonyms

Trisiloxane, 1,1,1,3,3,5,5,5-octamethyl-; Trisiloxane, octamethyl-; [ChemIDplus] 1,1,1,3,3,5,5,5-Octamethyltrisiloxane; [Merck Index] MDM; Dimethylbis(trimethylsiloxy)silane; Pentamethyl(trimethylsiloxy)disiloxane; Pentamethyl(trimethylsilyloxy)disiloxane; L3; Trisiloxan; [ToxPlanet: Government of Canada - Chemicals Management Plan] UN1993

Category

Metalloid Compounds (Silicon)

Description

Liquid; [Merck Index] Colorless odorless liquid; [Acros Organics MSDS]

Sources/Uses

Used as a base for extreme temperature silicone oils/fluids and as a foam suppressant in petroleum lubricating oils; [Merck Index] Used mainly to make polydimethylsiloxane (PDMS) polymers, oligomers, and mixtures; Also used to make basic chemicals, paints, coatings, adhesives, soaps, cleaning compounds, toiletries, plastics, semiconductors, and other electronic components, and in building construction, lubricants, diluents, solvents, and cosmetics; [ToxPlanet: Government of Canada - Chemicals Management Plan]

Comments

Causes histopathological liver changes at 1,000 mg/kg/day in 28-day oral study of rats; [ToxPlanet: EPA - TSCATS] No evidence of skin sensitization in human patch test studies; [ToxPlanet: Government of Canada - Chemicals Management Plan] May cause temporary redness and discomfort on eye contact; May cause CNS depression; [Acros Organics MSDS] See "Tetrakis(trimethylsiloxy)silane." See "Dimethoxydimethylsilane."

Exposure Assessment
Vapor Pressure

3.34 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Flammable liquid, n.o.s."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: