Agent Name

Pentamidine isethionate

CAS Number

140-64-7

Formula

C19-H24-N4-O2.2C2-H6-O4-S

Major Category

Other Uses

Synonyms

2512 R.P.; 4,4'-(Pentamethylenedioxy)-dibenzamidine bis(2-hydroxyethanesulfonate); 4,4'-Diamidino-alpha,omega-diphenoxypentane isethionate; 4,4'-Diamidinodiphenoxypentane di(beta-hydroxyethanesulfonate); Diamidine; Lomidin; Lomidine; Lomidine isoethionate; M & B 800; Nebupent; Pentacarinat; Pentam 300; Pentamidine diisethionate; Pentamidine isethionate; Pneumopent; R.P. 2512; RP 2512; USAF XR-10; WR 4931; p,p'-(Pentamethylenedioxy)dibenzamidine bis(beta-hydroxyethanesulfonate); [ChemIDplus]

Category

Pharmaceuticals

Sources/Uses

"Pentamidine (formulated as a salt, pentamidine diisethionate or dimesilate) is an antimicrobial medication given for prevention and treatment of Pneumocystis pneumonia (PCP) caused by Pneumocystis jirovecii (formerly known as Pneumocystis carinii), a severe interstitial type of pneumonia often seen in patients with HIV infection. The drug is also the mainstay of treatment for stage I infection with Trypanosoma brucei gambiense (West African Trypanosomiasis)." [Wikipedia]

Comments

Immunological contact urticaria documented in pharmaceutical and healthcare workers; [Kanerva, p. 219]

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: