Agent Name

Diethylene glycol dimethyl ether

Alternative Name

Diglyme

CAS Number

111-96-6

Formula

C6-H14-O3

Major Category

Solvents

Synonyms

(2-Methoxyethyl) ether; 1,1'-Oxybis(2-methoxyethane); 2,5,8-Trioxanonane; 2-(2-Methoxyethoxy)-1-methoxyethane; Bis(2-methoxyethyl) ether; Bis(2-methoxyethyl)ether; Di(2-Methoxyethyl) ether; Diethyl glycol dimethyl ether; Diethylene glycol dimethyl ether; Diglycol methyl ether; Diglyme; Dimethyl carbitol; Ethane, 1,1'-oxybis(2-methoxy-; Ethanol, 2,2'-oxybis-, dimethyl ether; Ether, bis(2-methoxyethyl); Glyme 2; Methyldiglyme; Poly-Solv; [ChemIDplus] DEGDME; [ICSC]

Category

Glycol Ethers (Glymes)

Description

Clear liquid with a pleasant odor; [CAMEO]

Sources/Uses

Used as a solvent and chemical intermediate; [Merck Index] Used in the coating industry and in photolithography to make semiconductor chips; Also used in adhesives, sealants, and automotive care products; [Reference #1]

Comments

Toxic after ingestion; [CAMEO] A reproductive toxin in experimental animals; [HSDB] A possible human reproductive toxin based on animal testing; A skin, eye, and respiratory tract irritant; [ICSC] Low acute toxicity to mammals but evidence of developmental toxicity and toxicity to blood forming organs in repeated-dose animal testing; A potential reproductive toxin; [Reference #1] Labeled as "May impair fertility" and "May cause harm to the unborn child" by EU regulations; [Glycol Ethers Online]

Exposure Assessment
MAK

5 ppm

Vapor Pressure

2.96 mm Hg

Explanatory Notes

Flash point equals 153 to 158 degrees F; boiling point equals 321 to 324 degrees F; [CAMEO]

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Reproductive Toxin

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: