| Agent Name | Diethylene glycol monoethyl ether |
|---|---|
| Alternative Name | DEGEE |
| CAS Number | 111-90-0 |
| Formula | C6-H14-O3 |
| Major Category | Solvents |
| Synonyms | 2-(2-Ethoxyethoxy) ethanol; 2-(2-Ethoxyethoxy)ethanol; 3,6-Dioxa-1-octanol; 3,6-Dioxa-1-oktanol [Czech]; Aethyldiaethylenglycol [German]; Carbitol; Carbitol cellosolve; Carbitol solvent; DEGMEE; Diethylene glycol ethyl ether; Diethylene glycol monoethyl ether; Diethyleneglycol monoethyl ether; Diglycol monoethyl ether; Dioxitol; Dowanol 17; Dowanol DE; Ektasolve DE; Ethanol, 2,2'-oxybis-, monoethyl ether; Ethanol, 2-(2-ethoxyethoxy)-; Ethoxy diglycol; Ethyl carbitol; Ethyl diethylene glycol; Ethyl digol; Ethylene diglycol monoethyl ether; Karbitol [Czech]; Losungsmittel APV; Monoethyl ether of diethylene glycol; PM 1799; Poly-Solv DE; Solvolsol; Transcutol; Transcutol P; [ChemIDplus] DiEGEE; [AIHA] NA8027 |
| Category | Glycol Ethers (E Series) |
| Description | A clear slightly viscous liquid with a mild pleasant odor; [CAMEO] |
| Sources/Uses | Used in lubricating oil and braking fluid; [ChemIDplus] Used as a solvent for cellulose esters, lacquers, varnishes, enamels, dyestuffs, wood stains, gums, and resins; [Merck Index, 1800] Used in textile printing; [CHEMINFO] Used in photography (solvent for color processing); [www.ci.tucson.az.us/arthazards/medium.html] |
| Comments | In oral or dermal doses >800-1000 mg/kg/day, animals exhibit CNS depression and changes to liver and kidneys, but no significant developmental toxicity; [Reference #1] Adverse effects not expected, unless workers are exposed to mists of heated liquid; [CHEMINFO] An eye irritant; [ICSC] Adverse effects in animal feeding studies include injury to the CNS, liver, kidneys, red blood cells, and reproductive system. [HSDB] Poorly absorbed through the skin; [AIHA] See "Glycol Ethers." |
| Reference Link | |
| Exposure Assessment | |
| MAK | 50 mg/m3, inhalable fraction |
| WEEL | 25 ppm |
| Vapor Pressure | 0.12 mm Hg |
| Odor Threshold Low | 0.21 mg/m3 |
| Lethal Concentration | LC50 (rat) > 5240 mg/m3/4H |
| Explanatory Notes | Flash point equals 205 degrees F; boiling point equals 396 degrees F; [CAMEO] Odor threshold from CHEMINFO; |
| Flammability (NFPA) | |
| Adverse Effects | |
| Neurotoxin | CNS Solvent Syndrome |
| Hepatotoxin | Hepatotoxin, Secondary |
| Nephrotoxin | Yes |
| Reproductive Toxin | Yes |
| Links to Other NLM Databases | |
| Health Studies | Human Health Effects from Hazardous Substances Data Bank: |
| Toxicity Information | |
| Chemical Information | |
| Related Information in HazMap | |
| Diseases | Occupational diseases associated with exposure to this agent: |
| Processes | Industrial Processes with risk of exposure: |
Agent Name
Diethylene glycol monoethyl ether
Alternative Name
DEGEE
CAS Number
111-90-0
Formula
C6-H14-O3
Major Category
Solvents
Synonyms
2-(2-Ethoxyethoxy) ethanol; 2-(2-Ethoxyethoxy)ethanol; 3,6-Dioxa-1-octanol; 3,6-Dioxa-1-oktanol [Czech]; Aethyldiaethylenglycol [German]; Carbitol; Carbitol cellosolve; Carbitol solvent; DEGMEE; Diethylene glycol ethyl ether; Diethylene glycol monoethyl ether; Diethyleneglycol monoethyl ether; Diglycol monoethyl ether; Dioxitol; Dowanol 17; Dowanol DE; Ektasolve DE; Ethanol, 2,2'-oxybis-, monoethyl ether; Ethanol, 2-(2-ethoxyethoxy)-; Ethoxy diglycol; Ethyl carbitol; Ethyl diethylene glycol; Ethyl digol; Ethylene diglycol monoethyl ether; Karbitol [Czech]; Losungsmittel APV; Monoethyl ether of diethylene glycol; PM 1799; Poly-Solv DE; Solvolsol; Transcutol; Transcutol P; [ChemIDplus] DiEGEE; [AIHA] NA8027
Category
Glycol Ethers (E Series)
Description
A clear slightly viscous liquid with a mild pleasant odor; [CAMEO]
Sources/Uses
Used in lubricating oil and braking fluid; [ChemIDplus] Used as a solvent for cellulose esters, lacquers, varnishes, enamels, dyestuffs, wood stains, gums, and resins; [Merck Index, 1800] Used in textile printing; [CHEMINFO] Used in photography (solvent for color processing); [www.ci.tucson.az.us/arthazards/medium.html]
Comments
In oral or dermal doses >800-1000 mg/kg/day, animals exhibit CNS depression and changes to liver and kidneys, but no significant developmental toxicity; [Reference #1] Adverse effects not expected, unless workers are exposed to mists of heated liquid; [CHEMINFO] An eye irritant; [ICSC] Adverse effects in animal feeding studies include injury to the CNS, liver, kidneys, red blood cells, and reproductive system. [HSDB] Poorly absorbed through the skin; [AIHA] See "Glycol Ethers."
Reference Link
Exposure Assessment
MAK
50 mg/m3, inhalable fraction
WEEL
25 ppm
Vapor Pressure
0.12 mm Hg
Odor Threshold Low
0.21 mg/m3
Lethal Concentration
LC50 (rat) > 5240 mg/m3/4H
Explanatory Notes
Flash point equals 205 degrees F; boiling point equals 396 degrees F; [CAMEO] Odor threshold from CHEMINFO;
Flammability (NFPA)
Adverse Effects
Neurotoxin
CNS Solvent Syndrome
Hepatotoxin
Hepatotoxin, Secondary
Nephrotoxin
Yes
Reproductive Toxin
Yes
Links to Other NLM Databases
Health Studies
Human Health Effects from Hazardous Substances Data Bank:
Toxicity Information
Chemical Information
Related Information in HazMap
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: