| Agent Name | Diethylene glycol monoethyl ether |
|---|---|
| Alternative Name | DEGEE |
| CAS Number | 111-90-0 |
| Formula | C6-H14-O3 |
| Major Category | Solvents |
| Synonyms | 2-(2-Ethoxyethoxy) ethanol; 2-(2-Ethoxyethoxy)ethanol; 3,6-Dioxa-1-octanol; 3,6-Dioxa-1-oktanol [Czech]; Aethyldiaethylenglycol [German]; Carbitol; Carbitol cellosolve; Carbitol solvent; DEGMEE; Diethylene glycol ethyl ether; Diethylene glycol monoethyl ether; Diethyleneglycol monoethyl ether; Diglycol monoethyl ether; Dioxitol; Dowanol 17; Dowanol DE; Ektasolve DE; Ethanol, 2,2'-oxybis-, monoethyl ether; Ethanol, 2-(2-ethoxyethoxy)-; Ethoxy diglycol; Ethyl carbitol; Ethyl diethylene glycol; Ethyl digol; Ethylene diglycol monoethyl ether; Karbitol [Czech]; Losungsmittel APV; Monoethyl ether of diethylene glycol; PM 1799; Poly-Solv DE; Solvolsol; Transcutol; Transcutol P; [ChemIDplus] DiEGEE; [AIHA] NA8027 |
| Category | Glycol Ethers (E Series) |
| Description | A clear slightly viscous liquid with a mild pleasant odor; [CAMEO] |
| Sources/Uses | Used in lubricating oil and braking fluid; [ChemIDplus] Used as a solvent for cellulose esters, lacquers, varnishes, enamels, dyestuffs, wood stains, gums, and resins; [Merck Index, 1800] Used in textile printing; [CHEMINFO] Used in photography (solvent for color processing); [www.ci.tucson.az.us/arthazards/medium.html] |
| Comments | In oral or dermal doses >800-1000 mg/kg/day, animals exhibit CNS depression and changes to liver and kidneys, but no significant developmental toxicity; [Reference #1] Adverse effects not expected, unless workers are exposed to mists of heated liquid; [CHEMINFO] An eye irritant; [ICSC] Adverse effects in animal feeding studies include injury to the CNS, liver, kidneys, red blood cells, and reproductive system. [HSDB] Poorly absorbed through the skin; [AIHA] See "Glycol Ethers." |
| Reference Link | |
| Exposure Assessment | |
| MAK | 50 mg/m3, inhalable fraction |
| WEEL | 25 ppm |
| Vapor Pressure | 0.12 mm Hg |
| Odor Threshold Low | 0.21 mg/m3 |
| Lethal Concentration | LC50 (rat) > 5240 mg/m3/4H |
| Explanatory Notes | Flash point equals 205 degrees F; boiling point equals 396 degrees F; [CAMEO] Odor threshold from CHEMINFO; |
| Adverse Effects | |
| Neurotoxin | CNS Solvent Syndrome |
| Hepatotoxin | Hepatotoxin, Secondary |
| Nephrotoxin | Yes |
| Reproductive Toxin | Yes |
| Links to Other NLM Databases | |
| Health Studies | Human Health Effects from Hazardous Substances Data Bank: |
| Toxicity Information | |
| Chemical Information | |
| Related Information in HazMap | |
| Diseases | Occupational diseases associated with exposure to this agent: |
| Processes | Industrial Processes with risk of exposure: |
Agent Name
Diethylene glycol monoethyl ether
Alternative Name
DEGEE
CAS Number
111-90-0
Formula
C6-H14-O3
Major Category
Solvents
Synonyms
2-(2-Ethoxyethoxy) ethanol; 2-(2-Ethoxyethoxy)ethanol; 3,6-Dioxa-1-octanol; 3,6-Dioxa-1-oktanol [Czech]; Aethyldiaethylenglycol [German]; Carbitol; Carbitol cellosolve; Carbitol solvent; DEGMEE; Diethylene glycol ethyl ether; Diethylene glycol monoethyl ether; Diethyleneglycol monoethyl ether; Diglycol monoethyl ether; Dioxitol; Dowanol 17; Dowanol DE; Ektasolve DE; Ethanol, 2,2'-oxybis-, monoethyl ether; Ethanol, 2-(2-ethoxyethoxy)-; Ethoxy diglycol; Ethyl carbitol; Ethyl diethylene glycol; Ethyl digol; Ethylene diglycol monoethyl ether; Karbitol [Czech]; Losungsmittel APV; Monoethyl ether of diethylene glycol; PM 1799; Poly-Solv DE; Solvolsol; Transcutol; Transcutol P; [ChemIDplus] DiEGEE; [AIHA] NA8027
Category
Glycol Ethers (E Series)
Description
A clear slightly viscous liquid with a mild pleasant odor; [CAMEO]
Sources/Uses
Used in lubricating oil and braking fluid; [ChemIDplus] Used as a solvent for cellulose esters, lacquers, varnishes, enamels, dyestuffs, wood stains, gums, and resins; [Merck Index, 1800] Used in textile printing; [CHEMINFO] Used in photography (solvent for color processing); [www.ci.tucson.az.us/arthazards/medium.html]
Comments
In oral or dermal doses >800-1000 mg/kg/day, animals exhibit CNS depression and changes to liver and kidneys, but no significant developmental toxicity; [Reference #1] Adverse effects not expected, unless workers are exposed to mists of heated liquid; [CHEMINFO] An eye irritant; [ICSC] Adverse effects in animal feeding studies include injury to the CNS, liver, kidneys, red blood cells, and reproductive system. [HSDB] Poorly absorbed through the skin; [AIHA] See "Glycol Ethers."
Reference Link
Exposure Assessment
MAK
50 mg/m3, inhalable fraction
WEEL
25 ppm
Vapor Pressure
0.12 mm Hg
Odor Threshold Low
0.21 mg/m3
Lethal Concentration
LC50 (rat) > 5240 mg/m3/4H
Explanatory Notes
Flash point equals 205 degrees F; boiling point equals 396 degrees F; [CAMEO] Odor threshold from CHEMINFO;
Adverse Effects
Neurotoxin
CNS Solvent Syndrome
Hepatotoxin
Hepatotoxin, Secondary
Nephrotoxin
Yes
Reproductive Toxin
Yes
Links to Other NLM Databases
Health Studies
Human Health Effects from Hazardous Substances Data Bank:
Toxicity Information
Chemical Information
Related Information in HazMap
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: