Agent Name | Diethylene glycol monoethyl ether |
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Alternative Name | DEGEE |
CAS Number | 111-90-0 |
Formula | C6-H14-O3 |
Major Category | Solvents |
Synonyms | 2-(2-Ethoxyethoxy) ethanol; 2-(2-Ethoxyethoxy)ethanol; 3,6-Dioxa-1-octanol; 3,6-Dioxa-1-oktanol [Czech]; Aethyldiaethylenglycol [German]; Carbitol; Carbitol cellosolve; Carbitol solvent; DEGMEE; Diethylene glycol ethyl ether; Diethylene glycol monoethyl ether; Diethyleneglycol monoethyl ether; Diglycol monoethyl ether; Dioxitol; Dowanol 17; Dowanol DE; Ektasolve DE; Ethanol, 2,2'-oxybis-, monoethyl ether; Ethanol, 2-(2-ethoxyethoxy)-; Ethoxy diglycol; Ethyl carbitol; Ethyl diethylene glycol; Ethyl digol; Ethylene diglycol monoethyl ether; Karbitol [Czech]; Losungsmittel APV; Monoethyl ether of diethylene glycol; PM 1799; Poly-Solv DE; Solvolsol; Transcutol; Transcutol P; [ChemIDplus] DiEGEE; [AIHA] NA8027 |
Category | Glycol Ethers (E Series) |
Description | A clear slightly viscous liquid with a mild pleasant odor; [CAMEO] |
Sources/Uses | Used in lubricating oil and braking fluid; [ChemIDplus] Used as a solvent for cellulose esters, lacquers, varnishes, enamels, dyestuffs, wood stains, gums, and resins; [Merck Index, 1800] Used in textile printing; [CHEMINFO] Used in photography (solvent for color processing); [www.ci.tucson.az.us/arthazards/medium.html] |
Comments | In oral or dermal doses >800-1000 mg/kg/day, animals exhibit CNS depression and changes to liver and kidneys, but no significant developmental toxicity; [Reference #1] Adverse effects not expected, unless workers are exposed to mists of heated liquid; [CHEMINFO] An eye irritant; [ICSC] Adverse effects in animal feeding studies include injury to the CNS, liver, kidneys, red blood cells, and reproductive system. [HSDB] Poorly absorbed through the skin; [AIHA] See "Glycol Ethers." |
Reference Link | |
Exposure Assessment | |
MAK | 50 mg/m3, inhalable fraction |
WEEL | 25 ppm |
Vapor Pressure | 0.12 mm Hg |
Odor Threshold Low | 0.21 mg/m3 |
Lethal Concentration | LC50 (rat) > 5240 mg/m3/4H |
Explanatory Notes | Flash point equals 205 degrees F; boiling point equals 396 degrees F; [CAMEO] Odor threshold from CHEMINFO; |
Flammability (NFPA) | |
Adverse Effects | |
Neurotoxin | CNS Solvent Syndrome |
Hepatotoxin | Hepatotoxin, Secondary |
Nephrotoxin | Yes |
Reproductive Toxin | Yes |
Links to Other NLM Databases | |
Health Studies | Human Health Effects from Hazardous Substances Data Bank: |
Toxicity Information | |
Chemical Information | |
Related Information in HazMap | |
Diseases | Occupational diseases associated with exposure to this agent: |
Processes | Industrial Processes with risk of exposure: |