Agent Name

Diethylene glycol monoethyl ether

Alternative Name

DEGEE

CAS Number

111-90-0

Formula

C6-H14-O3

Major Category

Solvents

Synonyms

2-(2-Ethoxyethoxy) ethanol; 2-(2-Ethoxyethoxy)ethanol; 3,6-Dioxa-1-octanol; 3,6-Dioxa-1-oktanol [Czech]; Aethyldiaethylenglycol [German]; Carbitol; Carbitol cellosolve; Carbitol solvent; DEGMEE; Diethylene glycol ethyl ether; Diethylene glycol monoethyl ether; Diethyleneglycol monoethyl ether; Diglycol monoethyl ether; Dioxitol; Dowanol 17; Dowanol DE; Ektasolve DE; Ethanol, 2,2'-oxybis-, monoethyl ether; Ethanol, 2-(2-ethoxyethoxy)-; Ethoxy diglycol; Ethyl carbitol; Ethyl diethylene glycol; Ethyl digol; Ethylene diglycol monoethyl ether; Karbitol [Czech]; Losungsmittel APV; Monoethyl ether of diethylene glycol; PM 1799; Poly-Solv DE; Solvolsol; Transcutol; Transcutol P; [ChemIDplus] DiEGEE; [AIHA] NA8027

Category

Glycol Ethers (E Series)

Description

A clear slightly viscous liquid with a mild pleasant odor; [CAMEO]

Sources/Uses

Used in lubricating oil and braking fluid; [ChemIDplus] Used as a solvent for cellulose esters, lacquers, varnishes, enamels, dyestuffs, wood stains, gums, and resins; [Merck Index, 1800] Used in textile printing; [CHEMINFO] Used in photography (solvent for color processing); [www.ci.tucson.az.us/arthazards/medium.html]

Comments

In oral or dermal doses >800-1000 mg/kg/day, animals exhibit CNS depression and changes to liver and kidneys, but no significant developmental toxicity; [Reference #1] Adverse effects not expected, unless workers are exposed to mists of heated liquid; [CHEMINFO] An eye irritant; [ICSC] Adverse effects in animal feeding studies include injury to the CNS, liver, kidneys, red blood cells, and reproductive system. [HSDB] Poorly absorbed through the skin; [AIHA] See "Glycol Ethers."

Reference Link

OECD SIDS: Diethylene glycol ethers - 2005

Exposure Assessment
MAK

50 mg/m3, inhalable fraction

WEEL

25 ppm

Vapor Pressure

0.12 mm Hg

Odor Threshold Low

0.21 mg/m3

Lethal Concentration

LC50 (rat) > 5240 mg/m3/4H

Explanatory Notes

Flash point equals 205 degrees F; boiling point equals 396 degrees F; [CAMEO] Odor threshold from CHEMINFO;

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Reproductive Toxin

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: