Agent Name

Ethylene glycol monophenyl ether

Alternative Name

EGPhE

CAS Number

122-99-6

Formula

C8-H10-O2

Major Category

Solvents

Synonyms

1-Hydroxy-2-phenoxyethane; 2-Fenoxyethanol [Czech]; 2-Hydroxyethyl phenyl ether; 2-Phenoxyethanol; 2-Phenoxyethyl alcohol; Arosol; Dowanol EP; Dowanol EPH; EGMPE; Emeressence 1160; Emery 6705; Ethanol, 2-phenoxy-; Ethylene glycol monophenyl ether; Ethylene glycol phenyl ether; Fenyl-cellosolve [Czech]; Fenylcelosolv [Czech]; Glycol monophenyl ether; Phenoxethol; Phenoxetol; Phenoxyethanol; Phenoxyethyl alcohol; Phenoxytol; Phenyl cellosolve; Phenylmonoglycol ether; Plastiazan-41 [Russian]; Rose ether; beta-Hydroxyethyl phenyl ether; [ChemIDplus] NA8027

Category

Glycol Ethers (E Series)

Description

Clear liquid with a pleasant odor; [CAMEO]

Sources/Uses

Used in perfumes, insect repellants, and antiseptics and to produce other organic chemicals; [Merck Index, 7257] Used as a solvent for inks, dyes, and cleaners; [HSDB]

Comments

Can cause corneal injury; [CAMEO] A skin irritant that can have adverse effects on the central and peripheral nervous systems; [ICSC] "Sensitization to this molecule is very rare." [Kanerva, p. 1825] No reproductive toxicity in animal studies, but liver and kidney injury occur at high doses. [MSDSonline] See "Glycol Ethers."

Exposure Assessment
MAK

1 ppm

Vapor Pressure

0.007 mm Hg

Explanatory Notes

Flash point equals 250 degrees F; boiling point equals 473 degrees F; [CAMEO] "Danger of cutaneous absorption"; [MAK]

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Skin Sensitizer

Yes

Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Reproductive Toxin

Yes

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: