Agent Name

Tripropylene glycol methyl ether

Alternative Name

TPGME

CAS Number

25498-49-1

Formula

C10-H22-O4

Major Category

Solvents

Synonyms

TPGME; [Glycol Ethers Online] (2-(2-Methoxymethylethoxy)methylethoxy)propanol; Arcosolv TPM; Dowanol TPM; O-Methyltripropylene glycol; Tripropylenglykolmonomethylether [Czech]; Propanol, (2-(2-methoxymethylethoxy)methylethoxy)-; Tripropylene glycol monomethyl ether; [ChemIDplus] Methyltripropylene glycol; TPM; Tripropyleneglycol (mono)methyl ether; [IUCLID] DOWANOL TPM GLYCOL ETHER; [Dow Chemical MSDS]

Category

Glycol Ethers (P Series)

Description

Colorless liquid with a mild odor; [CHRIS] Odor of ether; [Dow Chemical MSDS]

Sources/Uses

Permitted for use as an inert ingredient in non-food pesticide products; [EPA] Used in ballpoint pen inks, felt-tipped pens, inkpads, oven cleaners, coatings, rust, paint, and varnish removers, and in penetrating oils; [Reference #1]

Comments

May cause mild transient eye irritation; May have anesthetic effects; Prolonged or repeated overexposure may cause kidney and neural injury; [CHRIS] Commercial product is a mixture of up to 8 isomers due to the position of the internal ether being linked to either the primary or secondary carbon atoms; Category members demonstrate LOAELs of 1,000 mg/kg/day (highest tested dose) in 13-week oral studies of rats for increased liver and kidney weight without corresponding histopathology; No hematotoxicity observed; [Reference #1] May cause mild eye irritation; Excessive exposure may cause anesthetic or narcotic effects; [Dow Chemical MSDS]

Reference Link

OECD SIDS: Propylene Glycol Ethers - 2003

Exposure Assessment
Vapor Pressure

0.02 mm Hg

Lethal Concentration

LC50 (rat) > 200,000 mg/m3/1hr

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: