Agent Name

Calcitriol

CAS Number

32222-06-3

Formula

C27-H44-O3

Major Category

Biological Agents

Synonyms

(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1alpha,3beta,25-triol; 1,25-(OH)2D3; 1,25-DHCC; 1,25-Dihydroxycholecaliferol; 1,25-Dihydroxyvitamin D; 1-alpha,25-Dihydroxycholecalciferol; 1-alpha,25-Dihydroxyvitamin D3; 1alpha,25-Dihydroxycholecalciferol; 1alpha,25-Dihydroxyvitamin D; 9,10-Seco(5Z,7E)-5,7,10(19)-cholestatriene-1alpha,3beta,25-triol; Calcijex; Calcitriolum [INN-Latin]; DN 101; DN-101; Dihydroxyvitamin D3; Ro 21-5535; Ro 215535; Rocaltrol; Soltriol; Topitriol; U 49562; Vectical; 9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol, (1alpha,3beta,5Z,7E)-; Cholecalciferol, 1-alpha,25-dihydroxy-; [ChemIDplus] UN2811

Category

Vitamins and Derivatives

Description

White solid; [Merck Index]

Sources/Uses

Active form of vitamin D3 used therapeutically (calcium regulator, vitamin, antihyperparathyroid, antineoplastic, and antipsoriatic); [Merck Index] "Calcitriol, also called 1,25-dihydroxycholecalciferol or 1,25-dihydroxyvitamin D3, is the hormonally active form of vitamin D with three hydroxyl groups (abbreviated 1,25-(OH)2D3 or simply 1,25(OH)2D), . . " [Wikipedia]

Comments

May cause irritation; Highly toxic by ingestion; Toxic by inhalation; Targets the gastrointestinal tract, bone, kidney, and CNS; Suspected of causing toxicity to human reproduction; [Sigma-Aldrich MSDS] See "Vitamin D."

Exposure Assessment
Vapor Pressure

1.2E-12 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Toxic solid, organic, n.o.s."

Links to Other NLM Databases
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Human Health Effects from Hazardous Substances Data Bank:

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