Agent Name

(R,R)-Jacobsen's catalyst

CAS Number

138124-32-0

Formula

C36-H52-Cl-Mn-N2-O2

Major Category

Metals

Synonyms

(R,R)-(N,N'-Bis(3,5-di-tert-butyl-salicylidene)-1,2-cyclohexanediamine)manganese(III) chloride; [Merck Index] (R,R)-(-)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminomanganese(III) chloride; Jacobsen's catalyst; [Sigma-Aldrich MSDS]

Category

Manganese Compounds, Inorganic

Description

Dark brown powder; [Sigma-Aldrich MSDS]

Sources/Uses

Used as a chiral catalyst for the epoxidation of olefins; [Merck Index]

Comments

A skin and strong eye irritant; [Sigma-Aldrich MSDS] See "Manganese" and the linked occupational diseases.

Exposure Assessment
TLV (ACGIH)

0.02 mg/m3, as Mn (respirable fraction), 0.1 mg/m3, as Mn (inhalable fraction)

PEL (OSHA)

Ceiling(OSHA) = 5 mg/m3, as Mn

MAK

0.2 mg/m3, as Mn (inhalable fraction), 0.02 mg/m3, as Mn (respirable fraction)

Adverse Effects
Neurotoxin

Parkinson's Syndrome

Links to Other NLM Databases
Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: