Agent Name

1,1-Difluoro-1,2,2-trichloroethane

Alternative Name

HCFC-122

CAS Number

354-21-2

Formula

C2-H-Cl3-F2

Major Category

Solvents

Synonyms

1,1,2-Trichloro-2,2-difluoroethane; 1,2,2-Trichloro-1,1-difluoroethane; F 122 (halocarbon); FC 122; Freon 122; Frigen 122; HCFC 122; HCFC-122; R 122; Ucon fluorocarbon 122; Ethane, 1,1-difluoro-1,2,2-trichloro-; Ethane, 1,2,2-trichloro-1,1-difluoro-; Difluorotrichloroethane; [ChemIDplus] UN3082

Category

Chlorofluorocarbons

Description

Colorless liquid; [Alfa Aesar MSDS]

Comments

A mild to severe skin irritant; Causes somnolence and ataxia in oral lethal-dose studies of rats; Cause estrogenic effects, weight loss, fatty liver degeneration, other liver changes, changes in liver weight, and effects on hepatic microsomal mixed oxidase in 90-day intermittent inhalation studies of rats; [RTECS] May cause skin and eye irritation; [Alfa Aesar MSDS] See "1,1,1-Trifluoro-2,2-dichloroethane."

Exposure Assessment
Lethal Concentration

LCLo (rat) = 4,000 ppm/4hr

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Environmentally hazardous substances, liquid, n.o.s."

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: