Agent Name

1,1'-Methylenebis(4-isocyanatobenzene) homopolymer

CAS Number

25686-28-6

Formula

(C15-H10-N2-O2)x-

Major Category

Plastics & Rubber

Synonyms

Benzene, 1,1'-methylenebis(4-isocyanato-, homopolymer; [ChemIDplus] 4,4'-MDI homopolymer; 4,4-Diphenyl methanediisocyanate homopolymer; [EPA] 4,4'-Methylenediphenyl diisocyanate, oligomers; 1-Isocyanato-4-[(4-isocyanatophenyl)methyl]benzene homopolymer; [ToxPlanet: ECHA REACH Registrations]

Category

Polymers

Sources/Uses

Used in industrial flexible and rigid foams, coatings, adhesives, and sealants, in elastomer and other polymer production, in composite materials, and foundries; [ToxPlanet: ECHA REACH Registrations]

Comments

Causes acute pulmonary edema in 6-hour acute studies of rats; [RTECS] A skin and strong eye irritant; May cause skin and respiratory sensitization; Harmful by inhalation; Suspected carcinogen; [ToxPlanet: ECHA REACH Registrations] See "Methylenediphenyl diisocyanate."

Exposure Assessment
Lethal Concentration

LCLo (rat) = 490 mg/m3/4hr

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: