Agent Name

1,3-Diisopropenylbenzene

CAS Number

3748-13-8

Formula

C12-H14

Major Category

Other Classes

Synonyms

1,3-Bis(1-methylethenyl)benzene; Benzene, m-diisopropenyl-; m-Diisopropenylbenzene; m-DIPEB; Benzene, 1,3-bis(1-methylethenyl)-; m-Bis(1-methylvinyl)benzene; [ChemIDplus]

Category

Aromatic Hydrocarbons

Description

Liquid; [EPA ChAMP: Initial Risk-Based Prioritization] Clear light yellow liquid; [Sigma-Aldrich MSDS]

Sources/Uses

Used as an intermediate for other basic chemicals, diisocyanate monomers, and optical products; [EPA ChAMP: Initial Risk-Based Prioritization]

Comments

A mild skin and eye irritant in rabbits; A skin sensitizer in guinea pigs; No systemic, reproductive, or developmental toxicity observed in oral study of rats at doses up to 1,000 mg/kg/day; Increased absolute and relative liver weights (increased serum enzymes indicative of liver toxicity but without corresponding histopathology) observed in 4-week inhalation study of rats at 970 mg/m3/6hrs/day; [EPA ChAMP: Initial Risk-Based Prioritization] An irritant; May cause skin sensitization; [ToxPlanet: ECHA REACH Registrations] A skin and strong eye irritant; [Sigma-Aldrich MSDS] Search for (3748-13-8[EC/RN Number]) AND (sensitizer OR sensitization OR dermatitis OR allergic): no results; [PubMed]

Exposure Assessment
Vapor Pressure

0.16 mm Hg

Lethal Concentration

LC50 (rat) = 540-5,600 mg/m3/6hr

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.