Agent Name

1,3-Phenylene diisocyanate

CAS Number

123-61-5

Formula

C8-H4-N2-O2

Major Category

Plastics & Rubber

Synonyms

1,3-Diisocyanatobenzene; Benzene 1,3-diisocyanate; Benzene, 1,3-diisocyanato-; Benzene, m-diisocyanato-; Benzene-1,3-diisocyanate; m-Phenylene diisocyanate; m-Phenylene isocyanate; Nacconate 400; Isocyanic acid, m-phenylene ester; [ChemIDplus]

Category

Diisocyanates

Description

White solid with an irritating odor; [Alfa Aesar MSDS]

Comments

Intravenous LD50 (mouse) = 5,600 mg/kg; [RTECS] Hydrolyzed by water; A skin and strong eye irritant; May cause respiratory sensitization; Toxic by ingestion and inhalation; [Alfa Aesar MSDS] A lachrymator; [Sigma-Aldrich MSDS] See "DIISOCYANATES."

Exposure Assessment
Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Isocyanates, toxic, n.o.s."

Adverse Effects
Lacrimator

Yes

Asthma

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: