Agent Name

1,4-Dichloro-2-nitrobenzene

CAS Number

89-61-2

Formula

C6-H3-Cl2-N-O2

Major Category

Nitrogen Compounds

Synonyms

1-Nitro-2,5-dichlorobenzene; 2,5-Dichlornitrobenzen [Czech]; 2,5-Dichloronitrobenzene; 2,5-Dichloronitrobenzol; Benzene, 2,5-dichloronitro-; Nitro-p-dichlorobenzene; Benzene, 1,4-dichloro-2-nitro-; [ChemIDplus] 1,4Dichlor2nitrobenzol; 1,4Dichloro3nitrobenzene; 2,5DCNB; 2,5Dichlor1nitrobenzol; Benzol, 1,4dichlor2nitro; Nitropdichlorbenzol; Nitropdichlorobenzol; Nitropdiclorobenceno; pDichlornitrobenzol; [IUCLID] UN1578

Category

Nitros, Aromatic

Description

Yellow solid; [ICSC] Yellow crystals; [Sigma-Aldrich MSDS]

Sources/Uses

Used as an intermediate in the chemical industry; [IUCLID] Used to make pigments, pesticides, and UV absorbents; [HSDB]

Comments

No listed effects of short-term or long-term exposure (health effects have not been fully investigated); [ICSC] Can possibly induce methemoglobinemia; Can be absorbed through skin; Not a skin or eye irritant in rabbits; Not sensitizing in guinea pig maximization tests; No mortalities in rats exposed by inhalation to 47.6 mg/m3 for 7 hours; Increased liver weight (accompanied by hepatocellular hypertrophy), damage to the forestomach, increased bilirubin levels, and adverse male reproductive effects (depressed spermatogenesis) observed in 28-day oral study of rats; Cyanosis and methemoglobin formation observed in cats; [IUCLID] A mild skin and strong eye irritant; May induce methemoglobinemia; Harmful by ingestion and skin absorption; [Sigma-Aldrich MSDS] See "3,4-Dichloronitrobenzene."

Exposure Assessment
Vapor Pressure

0.00505 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Chloronitrobenzenes, solid."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.