Agent Name

Cadaverine

CAS Number

462-94-2

Formula

C5-H14-N2

Major Category

Nitrogen Compounds

Synonyms

1,5-Diaminopentane; 1,5-Pentamethylenediamine; Animal coniine; Cadaverin; Pentamethylenediamine; 1,5-Pentanediamine; [ChemIDplus] UN2735

Category

Amines, Aliphatic

Description

Colorless syrupy liquid that fumes in air; mp = 9 deg C; [Merck Index] Colorless hygroscopic liquid with an amine-like odor; [Alfa Aesar MSDS]

Sources/Uses

"A foul-smelling diamine formed by bacterial decarboxylation of lysine." [ChemIDplus] Biogenic polyamine present in cholera discharge; [Merck Index] Formed from decay of animal proteins; Used to make high polymers, as an intermediate, and in biological research; [HSDB] "Cadaverine is a foul-smelling diamine compound produced by protein hydrolysis during putrefaction of animal tissue." [Wikipedia]

Comments

A strong base that attracts carbon dioxide; A skin irritant and possible sensitizer; [Merck Index] Causes burns; [HSDB] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; [Alfa Aesar MSDS] Search for (462-94-2[EC/RN Number]) AND (sensitizer OR sensitization OR allergic OR dermatitis): no papers confirming skin sensitization; [PubMed] See "1,6-Diaminohexane."

Exposure Assessment
Vapor Pressure

1.01 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Polyamines, liquid, corrosive, n.o.s."

Flammability (NFPA)

2: High ambient temperature required

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.