Agent Name

Cadaverine

CAS Number

462-94-2

Formula

C5-H14-N2

Major Category

Nitrogen Compounds

Synonyms

1,5-Diaminopentane; 1,5-Pentamethylenediamine; Animal coniine; Cadaverin; Pentamethylenediamine; 1,5-Pentanediamine; [ChemIDplus] UN2735

Category

Amines, Aliphatic

Description

Colorless syrupy liquid that fumes in air; mp = 9 deg C; [Merck Index] Colorless hygroscopic liquid with an amine-like odor; [Alfa Aesar MSDS]

Sources/Uses

"A foul-smelling diamine formed by bacterial decarboxylation of lysine." [ChemIDplus] Biogenic polyamine present in cholera discharge; [Merck Index] Formed from decay of animal proteins; Used to make high polymers, as an intermediate, and in biological research; [HSDB] "Cadaverine is a foul-smelling diamine compound produced by protein hydrolysis during putrefaction of animal tissue." [Wikipedia]

Comments

A strong base that attracts carbon dioxide; A skin irritant and possible sensitizer; [Merck Index] Causes burns; [HSDB] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; [Alfa Aesar MSDS] Search for (462-94-2[EC/RN Number]) AND (sensitizer OR sensitization OR allergic OR dermatitis): no papers confirming skin sensitization; [PubMed] See "1,6-Diaminohexane."

Exposure Assessment
Vapor Pressure

1.01 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Polyamines, liquid, corrosive, n.o.s."

Adverse Effects
Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.