Agent Name

1-Aminoanthraquinone

CAS Number

82-45-1

Formula

C14-H9-N-O2

Major Category

Dyes

Synonyms

1-Amino-9,10-anthracenedione; 1-Amino-9,10-anthraquinone; 1-Aminoanthrachinon [Czech]; 9,10-Anthracenedione, 1-amino-; alpha-Aminoanthraquinone; alpha-Anthraquinonylamine; Diazo Fast Red AL; Anthraquinone, 1-amino-; [ChemIDplus] 1-Amino-9,10-anthracendion; 1-Aminoanthrachinon-9,10; alfa-Amminoantrhraquinone; alpha-Aminoanthrachinon [IUCLID]

Category

Anthraquinone Dyes

Description

Ruby-red solid; [Merck Index] Dark red to brown crystalline powder; [Acros Organics MSDS]

Sources/Uses

Used to make dyes and pharmaceuticals; [Merck Index]

Comments

An oral repeated-dose/reproductive/developmental toxicity study of rats demonstrated histopathological changes of the kidney and spleen, disappearance of nursing behavior, decreased pup viability on postnatal day 4, and NOAEL's for repeated-dose and reproductive toxicity of less than 40 mg/kg/day (lowest tested dose); No adverse effects on reproductive parameters or teratogenicity observed; [Reference #1] Not a skin or eye irritant in rabbits; [IUCLID] A mild eye irritant; Causes excitement, weight loss, and changes of the liver and kidney in inhalation studies of rats; Causes normocytic anemia, weight loss, and organ changes (liver, spleen, and heart) in 2-week oral studies of guinea pigs; [RTECS] A mild eye irritant; [Acros Organics MSDS] See "1-Amino-5-chloroanthraquinone."

Reference Link

OECD SIDS: 1-Aminoanthraquinone - 1996

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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