Agent Name

2,3-Dichloroaniline

CAS Number

608-27-5

Formula

C6-H5-Cl2-N

Major Category

Nitrogen Compounds

Synonyms

2,3-Dichlorobenzenamine; Aniline, 2,3-dichloro-; Benzenamine, 2,3-dichloro-; Aniline, 2,3-dichloro- (7CI,8CI); [ChemIDplus] 2,3-Dichlorophenylamine; [ToxPlanet: ECHA REACH Registrations] UN1590; UN3442 (dichloroanilines, solid)

Category

Amines, Aromatic

Description

Colorless solid or liquid; mp = 24 deg C; [ICSC] Solid; mp = 23-24 deg C; [Alfa Aesar MSDS]

Sources/Uses

Byproduct of 3,4-dichloroaniline production; Used in dyestuffs, pesticides, pharmaceuticals, and as a research chemical; [HSDB] Used as an intermediate; [ToxPlanet: ECHA REACH Registrations]

Comments

Causes somnolence, tremor, and weight loss in inhalation lethal-concentration studies of rats; [RTECS] Eye contact can cause redness and pain; May induce methemoglobinemia; Can be absorbed through skin; [ICSC] An irritant that may cause serious eye injury; May cause skin sensitization; Toxic by ingestion, inhalation, and skin absorption (may induce methemoglobinemia); Suspected mutagen and carcinogen; [ToxPlanet: ECHA REACH Registrations] An irritant; May induce methemoglobinemia; Highly toxic by ingestion, inhalation, and skin absorption; [Alfa Aesar MSDS] See "3,4-Dichloroaniline."

Exposure Assessment
Vapor Pressure

0.02 mm Hg

Lethal Concentration

LC50 (rat) > 8,047 mg/m3/4hr

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Dichloroanilines."

Adverse Effects
Skin Sensitizer

Yes

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: