Agent Name

2,3-Dichloroaniline

CAS Number

608-27-5

Formula

C6-H5-Cl2-N

Major Category

Nitrogen Compounds

Synonyms

2,3-Dichlorobenzenamine; Aniline, 2,3-dichloro-; Benzenamine, 2,3-dichloro-; Aniline, 2,3-dichloro- (7CI,8CI); [ChemIDplus] 2,3-Dichlorophenylamine; [ToxPlanet: ECHA REACH Registrations] UN1590; UN3442 (dichloroanilines, solid)

Category

Amines, Aromatic

Description

Colorless solid or liquid; mp = 24 deg C; [ICSC] Solid; mp = 23-24 deg C; [Alfa Aesar MSDS]

Sources/Uses

Byproduct of 3,4-dichloroaniline production; Used in dyestuffs, pesticides, pharmaceuticals, and as a research chemical; [HSDB] Used as an intermediate; [ToxPlanet: ECHA REACH Registrations]

Comments

Causes somnolence, tremor, and weight loss in inhalation lethal-concentration studies of rats; [RTECS] Eye contact can cause redness and pain; May induce methemoglobinemia; Can be absorbed through skin; [ICSC] An irritant that may cause serious eye injury; May cause skin sensitization; Toxic by ingestion, inhalation, and skin absorption (may induce methemoglobinemia); Suspected mutagen and carcinogen; [ToxPlanet: ECHA REACH Registrations] An irritant; May induce methemoglobinemia; Highly toxic by ingestion, inhalation, and skin absorption; [Alfa Aesar MSDS] See "3,4-Dichloroaniline."

Exposure Assessment
Vapor Pressure

0.02 mm Hg

Lethal Concentration

LC50 (rat) > 8,047 mg/m3/4hr

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Dichloroanilines."

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Skin Sensitizer

Yes

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: