Agent Name

2,4,6-Tri-tert-butylphenol

Alternative Name

2,4,6-Tris(1,1-dimethylethyl)phenol

CAS Number

732-26-3

Formula

C18-H30-O

Major Category

Other Classes

Synonyms

2,4,6-Tri-t-butylphenol; 2,4,6-Tri-tert-butyl-1-hydroxybenzene; 2,4,6-Tris(tert-butyl)phenol; Alkofen B; P 23; P23; TM02; 2,4,6-Tris(1,1-dimethylethyl)phenol; Phenol, 2,4,6-tri-tert-butyl- (6CI,7CI,8CI); Phenol, 2,4,6-tris(1,1-dimethylethyl)-; Phenol, 2,4,6-tri-tert-butyl-; [ChemIDplus] TBP; [HSDB] UN3077

Category

Phenols

Description

Solid; [HSDB] Yellow crystalline solid; [Sigma-Aldrich MSDS]

Sources/Uses

Used in Canada as an antioxidant in hydrocarbon fuels (gasoline, jet fuel, diesel, and biodiesel) and formerly as a lubricant additive; [ExPub: Government of Canada: Proposed Risk Management Approach] Also used as a starting material for 2,6-di-tert-butyl-4-methoxyphenol (antioxidant); [HSDB] Used as an intermediate; [ExPub: ECHA REACH Registrations]

Comments

Di- and tri-substituted mixed alkylphenols: Category members demonstrate moderate skin irritation; Low acute oral and moderate acute dermal toxicity; Evidence of liver toxicity in repeated-dose oral studies of rats; Developmental toxicity at doses producing marginal systemic toxicity in adults; No evidence of reproductive toxicity, mutagenicity, or carcinogenicity; [EPA ChAMP: Hazard Characterization] May cause irritation; Harmful by ingestion; [Sigma-Aldrich MSDS]

Exposure Assessment
Vapor Pressure

0.000661 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Environmentally hazardous substances, solid, n.o.s."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Other Information

No other related information on this agent was found.