Agent Name

Phenylethanolamine

CAS Number

7568-93-6

Formula

C8-H11-N-O

Major Category

Nitrogen Compounds

Synonyms

2-Hydroxyphenethylamine; 2-Amino-1-phenyl-1-ethanol; 2-Amino-1-phenylethanol; 2-Hydroxy-2-phenylethylamine; 2-Phenyl-2-hydroxyethylamine; alpha-(Aminomethyl)benzyl alcohol; Benzeneethanamine, beta-hydroxy-; beta-Hydroxy-beta-phenylethylamine; beta-Hydroxyphenethylamine; beta-Phenethanolamine; Ethanol, 2-amino-1-phenyl-; Ethylamine, beta-hydroxy-beta-phenyl-; Phenethylamine, beta-hydroxy-; Phenylethanolamin; Benzenemethanol, alpha-(aminomethyl)-; Benzenemethanol, alpha-(aminomethyl)- (VAN) (9CI); Benzyl alcohol, alpha-(aminomethyl)-; Benzyl alcohol, alpha-(aminomethyl)- (VAN) (8CI); [ChemIDplus] alpha-(Aminomethyl)benzenemethanol; [Merck Index]

Category

Ethanolamines

Description

Pale yellow solid; [Merck Index] Light yellow solidified mass or fragments; [Sigma-Aldrich MSDS]

Sources/Uses

"Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry." [ChemIDplus] Used as a stopping agent in polymerization of styrene-butadiene rubber, for hardening waxes, and to make pressor amines; The sulfate is used as a topical vasoconstrictor; [Merck Index] "As an organic compound, phenylethanolamine is a beta-hydroxylated phenethylamine that is also structurally related to a number of synthetic drugs such as phenylpropanolamine, and the ephedrine family of alkaloids/drugs. In common with these compounds, phenylethanolamine has strong cardiovascular activity and, under the name Apophedrin, has been used as a drug to produce topical vasoconstriction." [Wikipedia]

Comments

Intraperitoneal LD50 (mouse) = 250 mg/kg; [RTECS] A skin and strong eye irritant; [Sigma-Aldrich MSDS] See "N-Phenylethanolamine."

Exposure Assessment
Vapor Pressure

0.00132 mm Hg

Links to Other NLM Databases
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