Agent Name

Cysteamine hydrochloride

CAS Number

156-57-0

Formula

C2-H7-N-S.Cl-H

Major Category

Biological Agents

Synonyms

1-Amino-2-mercaptoethane hydrochloride; 1-Aminoethane-2-thiol hydrochloride; 2-Aminoethanethiol hydrochloride; 2-Mercaptoethylamine hydrochloride; 2-Mercaptoethylammonium chloride; 2-Thioethylamine hydrochloride; A-889; Bekaptan; beta-Mercaptoaethylamin chlorhydrat [German]; CI 9148; CI-9148; Cystaran; Cysteamine chlorohydrate; Cysteamine HCl; Cysteaminhydrochlorid [German]; Cysteaminium chloride; beta-Mercaptoethylamine hydrochloride; Ethylamine, 2-mercapto-, hydrochloride; Mercamine hydrochloride; Mercaptoethylamine hydrochloride; Merkamin hydrochloride; Cysteamine hydrochloride; Ethanethiol, 2-amino-, hydrochloride; Mercaptamine hydrochloride; [ChemIDplus]

Category

Amino Acids and Derivatives

Description

Solid; [Merck Index] White hygroscopic crystals; [Alfa Aesar MSDS]

Sources/Uses

Cysteamine is a natural antioxidant, precursor in taurine biosynthesis, and component of coenzyme A; Used in medical research (potent ulcerogen), as a drug (nephropathic cystinosis), and antidote (acetaminophen poisoning); [Merck Index] "A radiation-protective agent that oxidizes in air to form CYSTAMINE. It can be given intravenously or orally to treat radiation sickness. The bitartrate has been used for the oral treatment of nephropathic cystinosis." [ChemIDplus] Used as an intermediate; [ToxPlanet: ECHA REACH Registrations]

Comments

Causes burns to skin and eyes; A respiratory tract irritant; [ToxPlanet: ECHA REACH Registrations] Teratogenicity observed in oral study of rats in the absence of maternal toxicity; Developmental toxicity observed in intraperitoneal study of mice; [ToxPlanet: Shepard's Catalog of Teratogenic Agents] A skin and strong eye irritant; Harmful by ingestion; [Alfa Aesar MSDS]

Adverse Effects
Dermatotoxin

Skin Burns

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