Agent Name

Alizarin complexone

CAS Number

3952-78-1

Formula

C19-H15-N-O8

Major Category

Dyes

Synonyms

(((3,4-Dihydroxy-2-anthraquinonyl)methyl)imino)diacetic; acid dihydrate; 1,2-Dihydroxy-anthrachinon-3-methylen-iminodiessigsaeure; [German]; 3-Aminomethylalizarin-N,N-diacetic acid; Acetic acid, (((3,4-dihydroxy-2-anthraquinonyl)methyl)imino)di-; Alizarin Fluorine Blue; Alizarin complexon; Alizarin complexone; Alizarine Fluorine Blue; Alizarine complexon; Alizarine complexone; Alizarinkomplexon; Glycine, N-(carboxymethyl)-N-((9,10-dihydro-3,4-dihydroxy-9,10-dioxo-2-anthracenyl)methyl)-; [ChemIDplus]

Category

Anthraquinone Dyes

Description

Brown-orange crystals insoluble in water; [Sax]

Sources/Uses

"Metal indicators are organic compounds that form specifically colored metal ion complexes in aqueous media. These dye reactions can be employed for detection of the equivalence point in volumetry (complexometry), as well as for concentration determinations in colorimetry or photometry." [Ullmann] Alizarin complexone is used for the complexometric determination of Ba, Ca, Cd, Co, Hg, In, Pb, Sr, and Zn. It is used for the photometric determination of fluoride. [Ullmann]

Comments

Anthraquinones are toxic by ingestion: vomiting, diarrhea, kidney and liver damage, and coma; Deaths have been reported after chilldren ingested Rhamnus berries; [HSDB] "Has antiretroviral activity." [ChemIDplus]An irritant; Harmful by ingestion, inhalation, or skin absorption; Toxic if swallowed; [Aldrich MSDS]

Exposure Assessment
Explanatory Notes

mp = 181 deg C; [Sax]

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

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