Agent Name

2-Methyl-3-butyn-2-ol

CAS Number

115-19-5

Formula

C5-H8-O

Major Category

Other Classes

Synonyms

1,1-Dimethyl-2-propynol; 1,1-Dimethylpropargyl alcohol; 1,1-Dimethylpropynol; 1-Butyn-3-ol, 3-methyl-; 2-Hydroxy-2-methyl-3-butyne; 2-Methyl-2-butynol; 2-Methylbutyn-3-ol-2; 3-Methyl-1-butyn-3-ol; 3-Methyl-butin-(1)-ol-(3) [German]; 3-Methylbutynol; alpha,alpha-Dimethylpropargyl alcohol; Carbavane [Russian]; Dimethylacetylenecarbinol; Dimethylacetylenylcarbinol; Dimethylethynylcarbinol; Dimethylethynylmethanol; Ethynyldimethylcarbinol; 2-Methylbut-3-yn-2-ol; 3-Butyn-2-ol, 2-methyl-; 2-Methyl-2-hydroxy-3-butyne; 3-Methyl-butyn-3-ol; [ChemIDplus] Methylbutynol; [CAMEO] UN1987

Category

Alcohols and Polyols, Other

Description

Liquid; mp = 2.6 deg C; [Merck Index] Colorless liquid; [Alfa Aesar MSDS]

Sources/Uses

Has been used as a pheromone substitute in beetle control; [REPROTOX] Used as an intermediate, laboratory reagent, and in wood treatment; [ToxPlanet: ECHA REACH Registrations]

Comments

An eye but not skin irritant in rabbits; Not a skin sensitizer in guinea pig modified split adjuvant test; Developmental toxicity observed in rats at doses maternally toxic; [IUCLID] Causes somnolence, lung changes, ataxia, respiratory depression, and general anesthesia in inhalation lethal-concentration studies of mice; Oral LD50 (mouse) = 500 mg/kg; [RTECS] A skin and eye irritant; May cause smarting and reddening of skin if spilled and allowed to remain on clothes; High vapor concentrations may cause mild smarting of eyes and respiratory tract; [CHRIS] An eye irritant; [ICSC] May cause serious eye injury; Harmful by ingestion; [ToxPlanet: ECHA REACH Registrations] An irritant; Harmful by ingestion; [Alfa Aesar MSDS]

Exposure Assessment
Vapor Pressure

16 mm Hg

Lethal Concentration

LC50 (mouse) = 2,000 mg/m3

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Alcohols, n.o.s."

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: