Agent Name

2-Methyl-6-nitroaniline

CAS Number

570-24-1

Formula

C7-H8-N2-O2

Major Category

Nitrogen Compounds

Synonyms

1-Amino-2-methyl-6-nitrobenzene; 2-Methyl-6-nitro-benzenamine; 6-Nitro-o-toluidine; Benzenamine, 2-methyl-6-nitro-; [ChemIDplus] 2-Amino-3-methylnitrobenzene; 2-Amino-3-nitrotoluene; 6-Methyl-2-nitroaniline; 3-Nitro-2-aminotoluene; 2-Nitro-6-methylaniline; o-Toluidine, 6-nitro-; [CAMEO] 2-Methyl-6-nitrophenylamine; 3-Nitro-2-amino-toluene; 3-Nitro-2-amino-toluol; 3-Nitro-2-toluidine; [ToxPlanet: EC: SCCNFP] UN2660

Category

Nitroanilines

Description

Orange-yellow or brown solid; [CAMEO] Dark red solid; [ToxPlanet: EC: SCCNFP] Dark red crystalline solid; [Sigma-Aldrich MSDS]

Sources/Uses

Used in semi-permanent hair dyes; [ToxPlanet: EC: SCCNFP]

Comments

A mild skin and eye irritant in rabbits at 3% concentration in 1,2-propanediol; No evidence of skin sensitization in guinea pigs; Hepatotoxicity observed in 28-day oral studies of rats; No evidence of embryotoxicity or teratogenicity in rats; [ToxPlanet: EC: SCCNFP] May cause irritation; May induce methemoglobinemia; Toxic by ingestion, inhalation, and skin absorption; Targets the blood; [Sigma-Aldrich MSDS] See "2-Nitroaniline."

Exposure Assessment
Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Nitrotoluidines (mono)."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: