Agent Name

Squaric acid

Alternative Name

3,4-Dihydroxy-3-cyclobutene-1,2-dione

CAS Number

2892-51-5

Formula

C4-H2-O4

Major Category

Other Classes

Synonyms

1,2-Dihydroxycyclobutene-3,4-dione; 1,2-Diketo-3,4-dihydroxycyclobutene; 3,4-Dihydroxy-3-cyclobuten-1,2-dion; 3,4-Dihydroxy-3-cyclobutene-1,2-dione; 3,4-Dihydroxy-cyclobutene-1,2-dione; Cyclobutene-1,2-dione, 3,4-dihydroxy-; Dihydroxycyclobutenedione; Quadratic acid; Quadratsaeure; Squaric acid; 3-Cyclobutene-1,2-dione, 3,4-dihydroxy-; Cyclobutenedione, dihydroxy- (8CI); [ChemIDplus] 1,2-Dihydroxycyclobutenedione; Diketocyclobutenediol; [Merck Index]

Category

Aliphatic Ketones, Other

Description

Solid; [Merck Index] Gray crystalline solid; [Sigma-Aldrich MSDS]

Sources/Uses

Used to make pharmaceutical intermediates, squarylium dyes, and photoconducting squaraines; The dibutylester is used as a contact sensitizer in the treatment of alopecia and warts; [Merck Index]

Comments

A skin and strong eye irritant; May cause skin sensitization; [Sigma-Aldrich MSDS] Search for (2892-51-5[EC/RN Number]) AND (dermatitis OR allergic OR sensitizer OR sensitization): no reports of skin sensitization; [PubMed]

Links to Other NLM Databases
Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Other Information

No other related information on this agent was found.