Agent Name

3-Methyl-4-nitrophenol

CAS Number

2581-34-2

Formula

C7-H7-N-O3

Major Category

Nitrogen Compounds

Synonyms

2-Nitro-5-hydroxytoluene; 4-Nitro-1-hydroxy-3-methylbenzene; 4-Nitro-3-cresol; 4-Nitro-3-methylphenol; 4-Nitro-5-methylphenol; 4-Nitro-m-cresol; 5-Hydroxy-2-nitrotoluene; m-Cresol, 4-nitro-; Phenol, 3-methyl-4-nitro-; [ChemIDplus] UN2446

Category

Nitrophenols

Description

Dark yellow powder; [Sigma-Aldrich MSDS]

Sources/Uses

Used as an intermediate for pesticides; [Reference #1]

Comments

Transient excretion of glucose to urine observed in 6-month oral study of rats at 1,500 ppm (no other adverse effects observed); A preliminary reproductive/developmental study of rats demonstrated decreased locomotor activity and thrombi in the kidney, heart, and lung in males at 300 mg/kg/day, but no evidence of reproductive or developmental toxicity; Mutagenic effects observed in vitro and in vivo; [Reference #1] No adverse effects observed in mice orally administered 25 mg/kg during gestation; [ToxPlanet: Shepard's Catalog of Teratogenic Agents] An irritant that may cause serious eye injury; Harmful by ingestion, inhalation, and skin absorption; [Sigma-Aldrich MSDS]

Reference Link

OECD SIDS: 3-Methyl-4-nitrophenol - 1994

Exposure Assessment
Vapor Pressure

0.000632 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Nitrocresols, solid."

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Biomedical References

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Other Information

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