Agent Name

4-Chlorobenzoyl chloride

CAS Number

122-01-0

Formula

C7-H4-Cl2-O

Major Category

Toxic Gases & Vapors

Synonyms

Benzoyl chloride, 4-chloro-; [ChemIDplus] p-Chlorobenzoyl chloride; [RTECS] p-Chlorobenzoylchlorid; [ToxPlanet: ECHA REACH Registrations] PCOC; [Acros Organics MSDS] UN3129

Category

Acid Halides

Description

Clear colorless liquid; mp = 12-14 deg C; [Acros Organics MSDS]

Sources/Uses

Used to make fine chemicals; [ToxPlanet: ECHA REACH Registrations]

Comments

Causes irritant dermatitis and allergic anaphylaxis (multiple organ involvement) in 12-week intermittent intravenous studies of guinea pigs; [RTECS] A skin and eye irritant; May cause skin sensitization; [ToxPlanet: ECHA REACH Registrations] Hydrolyzed by water producing fumes and aqueous hydrogen chloride; Causes burns and lachrymation; Inhalation may cause corrosive injuries to respiratory tract; [Acros Organics MSDS]

Exposure Assessment
Vapor Pressure

0.05 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Water-reactive liquid, corrosive, n.o.s."

Adverse Effects
Skin Sensitizer

Yes

Lacrimator

Yes

Toxic Pneumonitis

Yes

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: