Agent Name

4-Isopropylaniline

Alternative Name

Cumidine

CAS Number

99-88-7

Formula

C9-H13-N

Major Category

Nitrogen Compounds

Synonyms

4-Amino-1-isopropylbenzene; 4-Aminocumene; Aniline, p-isopropyl-; beta-(4-Aminophenyl)propane; Cumene, p-amino-; p-Cumidine; p-Isopropylaniline; Benzenamine, 4-(1-methylethyl)-; Cumidine; [ChemIDplus] 4-(1-Methylethyl)benzenamine; [Merck Index] 1Amino4isopropylbenzene; 1Amino4isopropylbenzol; 4Aminoisopropylbenzene; Aniline, 4isopropyl; Benzolamin, 4(1methylethyl); pCumidin; pIsopropylanilin; [IUCLID]

Category

Amines, Aromatic

Description

Liquid; [Merck Index] Clear dark red liquid; [Sigma-Aldrich MSDS]

Sources/Uses

Used in the determination of tungsten; [Merck Index] Used in chemical synthesis; [IUCLID] Used to make fine and large scale chemicals; [ToxPlanet: ECHA REACH Registrations]

Comments

Hematological changes (including increased methemoglobin), increased spleen and liver weights, and histopathological changes of the bone marrow, spleen, and liver observed in oral repeated dose/reproductive/developmental study of rats with NOEL for parental animals of 6 mg/kg/day; This study also demonstrated decreased pup body weights and viability on day 4 of lactation but no evidence of reproductive toxicity; [ToxPlanet: JECDB] May induce methemoglobinemia; [IUCLID] Causes burns; Toxic by ingestion, inhalation, and skin absorption; [ToxPlanet: ECHA REACH Registrations] A skin and strong eye irritant; May induce methemoglobinemia; [Sigma-Aldrich MSDS]

Adverse Effects
Methemoglobinemia

Methemoglobinemia, Secondary

Dermatotoxin

Skin Burns

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