Agent Name

Calcium sulfate dihydrate

CAS Number

10101-41-4

Formula

O4-S.Ca.2H2-O

Major Category

Metals

Synonyms

Annaline; C.I. 77231; Compactrol; Light spar; Magnesia White; Mineral White; Native calcium sulfate; Precipitated calcium sulfate; Satin spar; Satinite; Sulfuric acid, calcium(2+) salt, dihydrate; Terra alba; Calcium(II) sulfate, dihydrate (1:1:2); Sulfuric acid, calcium salt (1:1), dihydrate; Calcium sulfate, dihydrate; [ChemIDplus] Gypsum; Alabaster; Selenite; [Merck Index] C.I. Pigment White 25; Gypsum stone; Land and plaster; [Reference #1]

Category

Metals, Inorganic Compounds

Description

White to slightly yellowish-white odorless solid; [Merck Index] Colorless hygroscopic solid; [Reference #1] White powder; [Sigma-Aldrich MSDS]

Sources/Uses

Used to make Portland cement, plaster of Paris, artificial marble, and porous polymers; Also used in soil treatment, paints/enamels (pigment), pharmaceuticals, paper, insecticide dusts, water treatment, polishing powders, and plaster casts; [Merck Index] Used in Portland cement retarders, tiles, plaster, wallboard, polishing powders, paints, paper, dyeing and calico printing, metallurgy (reduction of zinc minerals), food additives, desiccants, as source of sulfur and sulfuric acid, for drying industrial gases, solids, and organic liquids, as soil conditioner, in adhesives and binding agents, and to make other non-metallic mineral products; [Reference #1] Permitted for use as an inert ingredient in non-food pesticide products; [EPA]

Comments

Not a skin irritant in rabbits; No evidence of skin sensitization in guinea pigs; Decreased total protein, albumin, BUN, AST, ALT, and creatinine observed in males at 300 and 1,000 mg/kg/day in repeated-dose oral study of rats (possible effect on excretion, distribution, or metabolism relating to the kidney); No adverse effects observed in females at dose up to 1,000 mg/kg/day; No evidence of reproductive or developmental toxicity in rats at oral doses up to 1,000 mg/kg/day; No evidence of mutagenicity; [Reference #1] May cause mechanical irritation; Repeated or prolonged exposure to dust particles may cause lung effects; [ICSC] May cause irritation; [Sigma-Aldrich MSDS] See "Calcium sulfate." See "Gypsum."

Reference Link

OECD SIDS: Calcium sulfate, dihydrate - 2003

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

10 mg/m3, inhalable fraction

PEL (OSHA)

15 mg/m3(total dust), 5 mg/m3(respirable fraction)

MAK

4 mg/m3(inhalable fraction), 1.5 mg/m3(respirable fraction)

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Processes

Industrial Processes with risk of exposure: